Use of macrolides in pest control

ABSTRACT

In an embodiment the present invention is drawn to a a method of controlling wood pests and molluscs with a macrolide compound, wherein a pesticidally active amount of a pesticide comprising, as pesticidally active compound, at least one macrolide, in free form or agrochemically utilizable salt form, as active ingredient and at least one auxiliary is applied to the pests or their environment.

This application is a continuation of U.S. Ser. No. 13/109,775, filed May 17, 2011, which is a continuation of U.S. Ser. No. 11/927,825, filed on Oct. 30, 2007, which is a continuation of U.S. Ser. No. 10/939,589, filed on Sep. 13, 2004, now pending, which is a continuation of U.S. Ser. No. 10/256,365, filed Sep. 27, 2002, now U.S. Pat. No. 6,875,727, which is a continuation of U.S. Ser. No. 09/581,980, filed Jun. 20, 2000, now abandoned, which is a 371 filing of International Application No. PCT/EP98/08384, filed Dec. 21, 1998, the contents which are incorporated herein by reference.

The present invention relates to a method of controlling pests with macrolide compounds; more specifically to

(A) a novel method of controlling pests in and on transgenic crops of useful plants with a macrolide compound; (B) method of protecting plant propagation material and plant organs formed at a later point in time from attack by pests with such a macrolide compound; and (C) a method of controlling wood pests and molluscs with a macrolide compound.

Certain pest control methods are proposed in the literature. However, these methods are not fully satisfactory in the field of pest control, which is why there is a demand for providing further methods for controlling and combating pests, in particular insects and representatives of the order Acarina, or for protecting plants, especially crop plants. This object is achieved according to the invention by providing the present method.

(A) A first aspect of the present invention therefore relates to a method of controlling pests in crops of transgenic useful plants, such as, for example, in crops of maize, cereals, soya beans, tomatoes, cotton, potatoes, rice and mustard, characterized in that a pesticidal composition comprising a macrolide compound, in particular abamectin, in free form or in agrochemically useful salt form and at least one auxiliary is applied to the pests or their environment, in particular to the crop plant itself; to the use of the composition in question and to propagation material of transgenic plants which has been treated with it.

Surprisingly, it has now emerged that the use of a macrolide compound for controlling pests on transgenic useful plants which contain—for instance—one or more genes expressing a pesticidally, particularly insecticidally, acaricidally, nematocidally or fugicidally active ingredient, or which are tolerant against herbicides, has a synergistic effect. It is highly surprising that the use of a macrolide compound in combination with a transgenic plant exceeds the additive effect, to be expected in principle, on the pests to be controlled and thus extends the range of action of the macrolide compound and of the active principle expressed by the transgenic plant in particular in two respects:

In particular, it has been found, surprisingly, that within the scope of invention (A) the pesticidal activity of a macrolide compound in combination with the effect expressed by the transgenic useful plant, is not only additive in comparison with the pesticidal activities of the macrolide compound alone and of the transgenic crop plant alone, as can generally be expected, but that a synergistic effect is present. The term “synergistic”, however, is in no way to be understood in this connection as being restricted to the pesticidal activity, but the term also refers to other advantageous properties of the method according to the invention compared with the macrolide compound alone and the transgenic useful plant alone. Examples of such advantageous properties which may be mentioned are: extension of the pesticidal spectrum of action to other pests, for example to resistant strains; reduction in the application rate of the macrolide compound, or sufficient control of the pests with the aid of the compositions according to the invention even at an application rate of the macrolide compound alone and the transgenic useful plant alone are entirely ineffective; enhanced crop safety; improved quality of produce such as higher content of nutrient or oil, better fiber quality, enhanced shelf life, reduced content of toxic products such as mycotoxins, reduced content of residues or unfavorable constituents of any kind or better digestability; improved tolerance to unfavorable temperatures, draughts or salt content of water; enhanced assimilation rates such as nutrient uptake, water uptake and photosynthesis; favorable crop properties such as altered leaf area, reduced vegetative growth, increased yields, favorable seed shape/seed thickness or germination properties, altered colonialisation by saprophytes or epiphytes, reduction of senescense, improved phytoalexin production, improved of accelerated ripening, flower set increase, reduced boll fall and shattering, better attraction to beneficials and predators, increased pollination, reduced attraction to birds; or other advantages known to those skilled in the art.

The macrolide compounds used according to the inventions part (A), (B) and (C) are known to those skilled in the art. They are the classes of substances which are disclosed as milbemycins and avermectins, for example in U.S. Pat. No. 4,310,519, U.S. Pat. No. 5,077,298, German Offenlegungsschrift 2 717 040 or U.S. Pat. No. 4,427,663. These macrolides are also to be understood as meaning, in accordance with the invention, the derivatives of these substances, that is, for example, milbemycin oxime, moxidectin, ivermectin, abamectin, emamectin and doramectin, and also spinosyns of the formula

in which R₁, R₂, R₃, R₄, R₅ and R₆ independently of one another are hydrogen or a substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclyl group and the substructures A and B independently of one another denote that the two carbon atoms, to which each of these substructures is bonded, are linked by a single bond, by a double bond or by a single bond and an epoxy bridge, in free form or, if appropriate, in agrochemically utilizable salt form.

Within the scope of invention (A) abamectin is preferred. Abamectin is a mixture of avermectin B_(1a) and avermectin B_(1b) and is described, for example, in The Pesticide Manual, 10^(th) Ed. (1994), The British Crop Protection Council, London, page 3.

Also preferred within the scope of invention (A) is emamectin, which is 4″-De-oxy-4″-epi-N-methylamino avermectin B_(1b)/B_(1a), known from U.S. Pat. No. 4,874,749 and as MK-244 described in Journal of Organic Chemistry, Vol. 59 (1994), pages 7704-7708. Agrochemically especially useful salts of emamectin are described in U.S. Pat. No. 5,288,710.

Also preferred within the scope of invention (A) is the group of compounds consisting of the spinosyns and their derivatives; the group of compounds consisting of the naturally occurring spinosyns; or the group of compounds consisting of the derivatives of the naturally occurring spinosyns. Preferably, the active ingredient may comprise, within the scope of the subject-matter of the invention (A), spinosyn A; spinosyn D; or a mixture composed of spinosyn A and spinosyn D; especially preferred is spinosad. Spinosad is known from the “The Pesticide Manual”, 11^(th) Ed. (1997), The British Crop Protection Council, London, United Kingdom, pages 1272-1273.

The agrochemically compatible salts of the macrolide compounds are, for example, acid addition salts of inorganic and organic acids, in particular of hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, perchloric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, malonic acid, toluenesulfonic acid or benzoic acid. Preferred within the scope of the present invention is a composition known per se which comprises, as active ingredient, abamectin or spinosad in the free form, and emamectin as the benzoate salt.

The transgenic plants used according to the invention (A) are plants, or propagation material thereof, which are transformed by means of recombinant DNA technology in such a way that they are—for instance—capable of synthesizing selectively acting toxins as are known, for example, from toxin-producinginvertebrates, especially of the phylum Arthropoda, as can be obtained from Bacillus thuringiensis strains; or as are known from plants, such as lectins; or in the alternative capable of expressing a herbicidal or fungicidal resistance. Examples of such toxins, or transgenic plants which are capable of synthesizing such toxins, have been disclosed, for example, in EP-A-0 374 753, WO 93/07278, WO 95/34656, EP-A-0 427 529 and EP-A-451 878 and are incorporated by reference in the present application.

The methods for generating such transgenic plants are widely known to those skilled in the art and described, for example, in the publications mentioned above.

The toxins which can be expressed by such transgenic plants include, for example, toxins, such as proteins which have insecticidal properties and which are expressed by transgenic plants, for example Bacillus cereus proteins or Bacillus popliae proteins; or Bacillus thuringiensis endotoxins (B.t.), such as CryIA(a), CryIA(b), CryIA(c), CryIIA, CryIIIA, CryIIIB2 or CytA; VIP1; VIP2; VIP3; or insecticidal proteins of bacteria colonising nematodes like Photorhabdus spp or Xenorhabdus spp such as Photorhabdus luminescens, Xenorhabdus nematophilus etc.; proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin, papain inhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize RIP, abrin, luffin, saporin or bryodin; plant lectins such as pea lectins, barley lectins or snowdrop lectins; or agglutinins; toxins produced by animals, such as scorpion toxins, spider venoms, wasp venoms and other insect-specific neurotoxins; steroid metabolism enzymes, such as 3-hydroxysteroid oxidase, ecdysteroid UDP-glycosyl transferase, cholesterol oxidases, ecdysone inhibitors, HMG-COAreductase, ion channel blockers such as sodium and calcium, juvenile hormone esterase, diuretic hormone receptors, stilbene synthase, bibenzyl synthase, chitinases and glucanases.

Examples of known transgenic plants which comprise one or more genes which encode insecticidal resistance and express one or more toxins are the following: KnockOut® (maize), YieldGard® (maize); NuCOTN 33B® (cotton), Bollgard® (cotton), NewLeaf® (potatoes), NatureGard® and Protecta®.

The following table comprises further examples of targets and principles and crop phenotypes of transgenic crops which show tolerance against pests mainly insects, mites, nematodes, virus, bacteria and diseases or are tolerant to specific herbicides or classes of herbicides.

TABLE Al Crop: Maize Effected target or Crop phenotype/ expressed principle (s) Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as Sulfonylureas Dimboa biosynthesis (Bx1 gene) Helminthosporium turcicum, Rhopalosiphum maydis, Diplodia maydis, Ostrinia nubilalis, lepidoptera sp. CMIII (small basic maize seed plant pathogenes eg. fusarium, peptide alternaria, sclerotina Corn- SAFP (zeamatin) plant pathogenes eg. fusarium, alternaria, sclerotina, rhizoctonia, chaetomium, phycomyces Hm1 gene Cochliobolus Chitinases plant pathogenes Glucanases plant pathogenes Coat proteins viruses such as maize dwarf mosaic virus, maize chlorotic dwarf virus Bacillus thuringiensis toxins, lepidoptera, coleoptera, diptera, VIP 3, nematodes, eg. ostrinia nubilalis, Bacillus cereus toxins, heliothis zea, armyworms eg. Photorabdus and spodoptera Xenorhabdus toxins frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils 3-Hydroxysteroid oxidase lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils Peroxidase lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils Aminopeptidase inhibitors eg. lepidoptera, coleoptera, diptera, Leucine nematodes, eg. ostrinia nubilalis, aminopeptidase inhibitor (LAPI) heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils Limonene synthase corn rootworms Lectines lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils Protease Inhibitors eg. weevils, corn rootworm cystatin, patatin, virgiferin, CPTI ribosome inactivating protein lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils maize 5C9 polypeptide lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils HMG-CoA reductase lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils

TABLE A2 Crop Wheat Effected target or Crop phenotype/ expressed principle (s) Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase Aryloxyphenoxyalkanecarboxylic (ACCase) acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as Sulfonylureas Antifungal polypeptide AlyAFP plant pathogenes eg septoria and fusarioum glucose oxidase plant pathogenes eg. fusarium, septoria pyrrolnitrin synthesis genes plant pathogenes eg. fusarium, septoria serine/threonine kinases plant pathogenes eg. fusarium, septoria and other diseases Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria polypeptide and other diseases Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases plant pathogenes Glucanases plant pathogenes double stranded ribonuclease viruses such as BYDV and MSMV Coat proteins viruses such as BYDV and MSMV Bacillus thuringiensis toxins, VIP 3, lepidoptera, coleoptera, diptera, Bacillus cereus toxins, Photorabdus nematodes, and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, coleoptera, diptera, nematodes, Peroxidase lepidoptera, coleoptera, diptera, nematodes, Aminopeptidase inhibitors eg. lepidoptera, coleoptera, diptera, Leucine nematodes, aminopeptidase inhibitor Lectines lepidoptera, coleoptera, diptera, nematodes, aphids Protease Inhibitors eg. cystatin, lepidoptera, coleoptera, diptera, patatin, virgiferin, CPTI nematodes, aphids ribosome inactivating protein lepidoptera, coleoptera, diptera, nematodes, aphids HMG-CoA reductase lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg. spodoptera frugiperda, corn rootworms, sesamia sp., black cutworm, asian corn borer, weevils

TABLE A3 Crop Barley Effected target or Crop phenotype/ expressed principle (s) Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as Sulfonylureas Antifungal polypeptide AlyAFP plant pathogenes eg septoria and fusarioum glucose oxidase plant pathogenes eg. fusarium, septoria pyrrolnitrin synthesis genes plant pathogenes eg. fusarium, septoria serine/threonine kinases plant pathogenes eg. fusarium, septoria and other diseases Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria polypeptide and other diseases Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases plant pathogenes Glucanases plant pathogenes double stranded ribonuclease viruses such as BYDV and MSMV Coat proteins viruses such as BYDV and MSMV Bacillus thuringiensis toxins, VIP 3, lepidoptera, coleoptera, diptera, Bacillus cereus toxins, Photorabdus nematodes, and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, coleoptera, diptera, nematodes, Peroxidase lepidoptera, coleoptera, diptera, nematodes, Aminopeptidase inhibitors eg. lepidoptera, coleoptera, diptera, Leucine aminopeptidase inhibitor nematodes, Lectines lepidoptera, coleoptera, diptera, nematodes, aphids Protease Inhibitors eg. cystatin, lepidoptera, coleoptera, diptera, patatin, virgiferin, CPTI nematodes, aphids ribosome inactivating protein lepidoptera, coleoptera, diptera, nematodes, aphids HMG-CoA reductase lepidoptera, coleoptera, diptera, nematodes, aphids

TABLE A4 Crop Rice Effected target or Crop phenotype/ expressed principle (s) Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as Sulfonylureas Antifungal polypeptide AlyAFP plant pathogenes glucose oxidase plant pathogenes pyrrolnitrin synthesis genes plant pathogenes serine/threonine kinases plant pathogenes Phenylalanine ammonia lyase plant pathogenes eg bacterial leaf (PAL) blight and rice blast, inducible phytoalexins plant pathogenes eg bacterial leaf blight and rice blast B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight and rice blast receptor kinase plant pathogenes eg bacterial leaf blight and rice blast Hypersensitive response eliciting plant pathogenes polypeptide Systemic acquires resistance viral, bacterial, fungal, nematodal (SAR) genes pathogens Chitinases plant pathogenes eg bacterial leaf blight and rice blast Glucanases plant pathogenes double stranded ribonuclease viruses such as BYDV and MSMV Coat proteins viruses such as BYDV and MSMV Bacillus thuringiensis toxins, VIP 3, lepidoptera eg. stemborer, coleoptera eg Bacillus cereus toxins, Photorabdus rice water weevil, diptera, and rice hoppers Xenorhabdus toxins eg brown rice hopper 3-Hydroxysteroid oxidase lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper Peroxidase lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper Aminopeptidase inhibitors eg. lepidoptera eg. stemborer, Leucine coleoptera eg aminopeptidase inhibitor rice water weevil, diptera, rice hoppers eg brown rice hopper Lectines lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper Protease Inhibitors, lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper ribosome inactivating protein lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper HMG-CoA reductase lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper

TABLE A5 Crop Soya Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 Xenobiotics and herbicides such as SU1 or selection Sulfonylureas Antifungal polypeptide AlyAFP bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot oxalate oxidase bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot glucose oxidase bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot pyrrolnitrin synthesis genes bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot serine/threonine kinases bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot Phenylalanine ammonia lyase bacterial and fungal pathogens such (PAL) as fusarium, sclerotinia, stemrot phytoalexins plant pathogenes eg bacterial leaf blight and rice blast B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight and rice blast receptor kinase bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot Hypersensitive response eliciting plant pathogenes polypeptide Systemic acquires resistance viral, bacterial, fungal, nematodal (SAR) genes pathogens Chitinases bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot Glucanases bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot double stranded ribonuclease viruses such as BPMV and SbMV Coat proteins viruses such as BYDV and MSMV Bacillus thuringiensis toxins, lepidoptera, coleoptera, aphids VIP 3, Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, coleoptera, aphids Peroxidase lepidoptera, coleoptera, aphids Aminopeptidase inhibitors lepidoptera, coleoptera, aphids eg. Leucine aminopeptidase inhibitor Lectines lepidoptera, coleoptera, aphids Protease Inhibitors eg virgiferin lepidoptera, coleoptera, aphids ribosome inactivating protein lepidoptera, coleoptera, aphids HMG-CoA reductase lepidoptera, coleoptera, aphids Barnase nematodes eg root knot nematodes and cyst nematodes Cyst nematode hatching stimulus cyst nematodes Antifeeding principles nematodes eg root knot nematodes and cyst nematodes

TABLE A6 Crop Potatoes Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as or selection Sulfonylureas Polyphenol oxidase or Polyphenol blackspot bruise oxidase antisense Metallothionein bacterial and fungal pathogens such as phytophtora Ribonuclease Phytophtora, Verticillium, Rhizoctonia Antifungal polypeptide AlyAFP bacterial and fungal pathogens such as phytophtora oxalate oxidase bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia glucose oxidase bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia pyrrolnitrin synthesis genes bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia serine/threonine kinases bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia Cecropin B bacteria such as corynebacterium sepedonicum, Erwinia carotovora Phenylalanine ammonia lyase bacterial and fungal pathogens such (PAL) as Phytophtora, Verticillium, Rhizoctonia phytoalexins bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia B-1,3-glucanase antisense bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia receptor kinase bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia Hypersensitive response eliciting bacterial and fungal pathogens such polypeptide as Phytophtora, Verticillium, Rhizoctonia Systemic acquires resistance viral, bacterial, fungal, nematodal (SAR) genes pathogens Chitinases bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia Barnase bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia Disease resistance response bacterial and fungal pathogens such gene 49 as Phytophtora, Verticillium, Rhizoctonia trans aldolase antisense blackspots Glucanases bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia double stranded ribonuclease viruses such as PLRV, PVY and TRV Coat proteins viruses such as PLRV, PVY and TRV 17 kDa or 60 kDa protein viruses such as PLRV, PVY and TRV Nuclear inclusion proteins viruses such as PLRV, PVY and TRV eg. a or b Pseudoubiquitin viruses such as PLRV, PVY and TRV Replicase viruses such as PLRV, PVY and TRV Bacillus thuringiensis toxins, coleoptera eg colorado potato beetle, VIP 3, Bacillus cereus toxins, aphids Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase coleoptera eg colorado potato beetle, aphids Peroxidase coleoptera eg colorado potato beetle, aphids Aminopeptidase inhibitors eg. coleoptera eg colorado potato beetle, Leucine aminopeptidase inhibitor aphids stilbene synthase coleoptera eg colorado potato beetle, aphids Lectines coleoptera eg colorado potato beetle, aphids Protease Inhibitors eg cystatin, coleoptera eg colorado potato beetle, patatin aphids ribosome inactivating protein coleoptera eg colorado potato beetle, aphids HMG-CoA reductase coleoptera eg colorado potato beetle, aphids Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes Antifeeding principles nematodes eg root knot nematodes and cyst nematodes

TABLE A7 Crop Tomatoes Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase Aryloxyphenoxyalkanecarboxylic acids, (ACCase) cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl Phosphinothricin transferase O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase Inhibitors of IMP and AMP synthesis (ADSL) Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl- Glyphosate or sulfosate 3phosphoshikimate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 Xenobiotics and herbicides such as SU1 or selection Sulfonylureas Polyphenol oxidase or blackspot bruise Polyphenol oxidase antisense Metallothionein bacterial and fungal pathogens such as phytophtora Ribonuclease Phytophtora, Verticillium, Rhizoctonia Antifungal polypeptide bacterial and fungal pathogens such as AlyAFP bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. oxalate oxidase bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. glucose oxidase bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. pyrrolnitrin synthesis genes bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. serine/threonine kinases bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Cecropin B bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Phenylalanine ammonia lyase bacterial and fungal pathogens such as (PAL) bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Cf genes eg. Cf 9 Cf5 Cf4 Cf2 leaf mould Osmotin alternaria solani Alpha Hordothionin bacteria Systemin bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Polygalacturonase inhibitors bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Prf regulatory gene bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. I2 Fusarium resistance locus fusarium phytoalexins bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. B-1,3-glucanase antisense bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. receptor kinase bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Hypersensitive response bacterial and fungal pathogens such as eliciting polypeptide bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Systemic acquires resistance viral, bacterial, fungal, nematodal (SAR) genes pathogens Chitinases bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Barnase bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. Glucanases bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc. double stranded ribonuclease viruses such as PLRV, PVY and ToMoV Coat proteins viruses such as PLRV, PVY and ToMoV 17 kDa or 60 kDa protein viruses such as PLRV, PVY and ToMoV Nuclear inclusion proteins eg. viruses such as PLRV, PVY and ToMoV a or b or Nucleoprotein TRV Pseudoubiquitin viruses such as PLRV, PVY and ToMoV Replicase viruses such as PLRV, PVY and ToMoV Bacillus thuringiensis toxins, lepidoptera eg heliothis, whiteflies VIP 3, Bacillus cereus toxins, aphids Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera eg heliothis, whiteflies aphids Peroxidase lepidoptera eg heliothis, whiteflies aphids Aminopeptidase inhibitors lepidoptera eg heliothis, whiteflies aphids eg. Leucine aminopeptidase inhibitor Lectines lepidoptera eg heliothis, whiteflies aphids Protease Inhibitors eg cystatin, lepidoptera eg heliothis, whiteflies aphids patatin ribosome inactivating protein lepidoptera eg heliothis, whiteflies aphids stilbene synthase lepidoptera eg heliothis, whiteflies aphids HMG-CoA reductase lepidoptera eg heliothis, whiteflies aphids Cyst nematode hatching cyst nematodes stimulus Barnase nematodes eg root knot nematodes and cyst nematodes Antifeeding principles nematodes eg root knot nematodes and cyst nematodes

TABLE A8 Crop Peppers Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as or selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens oxidase antisense Metallothionein bacterial and fungal pathogens Ribonuclease bacterial and fungal pathogens Antifungal polypeptide AlyAFP bacterial and fungal pathogens oxalate oxidase bacterial and fungal pathogens glucose oxidase bacterial and fungal pathogens pyrrolnitrin synthesis genes bacterial and fungal pathogens serine/threonine kinases bacterial and fungal pathogens Cecropin B bacterial and fungal pathogens rot, leaf mould etc. Phenylalanine ammonia lyase bacterial and fungal pathogens (PAL) Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens Osmotin bacterial and fungal pathogens Alpha Hordothionin bacterial and fungal pathogens Systemin bacterial and fungal pathogens Polygalacturonase inhibitors bacterial and fungal pathogens Prf regulatory gene bacterial and fungal pathogens I2 Fusarium resistance locus fusarium phytoalexins bacterial and fungal pathogens B-1,3-glucanase antisense bacterial and fungal pathogens receptor kinase bacterial and fungal pathogens Hypersensitive response eliciting bacterial and fungal pathogens polypeptide Systemic acquires resistance viral, bacterial, fungal, nematodal (SAR) genes pathogens Chitinases bacterial and fungal pathogens Barnase bacterial and fungal pathogens Glucanases bacterial and fungal pathogens double stranded ribonuclease viruses such as CMV, TEV Coat proteins viruses such as CMV, TEV 17 kDa or 60 kDa protein viruses such as CMV, TEV Nuclear inclusion proteins eg. viruses such as CMV, TEV a or b or Nucleoprotein Pseudoubiquitin viruses such as CMV, TEV Replicase viruses such as CMV, TEV Bacillus thuringiensis toxins, lepidoptera, whiteflies aphids VIP 3, Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, whiteflies aphids Peroxidase lepidoptera, whiteflies aphids Aminopeptidase inhibitors eg. lepidoptera, whiteflies aphids Leucine aminopeptidase inhibitor Lectines lepidoptera, whiteflies aphids Protease Inhibitors eg cystatin, lepidoptera, whiteflies aphids patatin ribosome inactivating protein lepidoptera, whiteflies aphids stilbene synthase lepidoptera, whiteflies aphids HMG-CoA reductase lepidoptera, whiteflies aphids Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes Antifeeding principles nematodes eg root knot nematodes and cyst nematodes

TABLE A9 Crop Grapes Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like oxidase antisense Botrytis and powdery mildew Metallothionein bacterial and fungal pathogens like Botrytis and powdery mildew Ribonuclease bacterial and fungal pathogens like Botrytis and powdery mildew Antifungal polypeptide AlyAFP bacterial and fungal pathogens like Botrytis and powdery mildew oxalate oxidase bacterial and fungal pathogens like Botrytis and powdery mildew glucose oxidase bacterial and fungal pathogens like Botrytis and powdery mildew pyrrolnitrin synthesis genes bacterial and fungal pathogens like Botrytis and powdery mildew serine/threonine kinases bacterial and fungal pathogens like Botrytis and powdery mildew Cecropin B bacterial and fungal pathogens like Botrytis and powdery mildew Phenylalanine ammonia lyase bacterial and fungal pathogens like (PAL) Botrytis and powdery mildew Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like Botrytis and powdery mildew Osmotin bacterial and fungal pathogens like Botrytis and powdery mildew Alpha Hordothionin bacterial and fungal pathogens like Botrytis and powdery mildew Systemin bacterial and fungal pathogens like Botrytis and powdery mildew Polygalacturonase inhibitors bacterial and fungal pathogens like Botrytis and powdery mildew Prf regulatory gene bacterial and fungal pathogens like Botrytis and powdery mildew phytoalexins bacterial and fungal pathogens like Botrytis and powdery mildew B-1,3-glucanase antisense bacterial and fungal pathogens like Botrytis and powdery mildew receptor kinase bacterial and fungal pathogens like Botrytis and powdery mildew Hypersensitive response eliciting bacterial and fungal pathogens like polypeptide Botrytis and powdery mildew Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases bacterial and fungal pathogens like Botrytis and powdery mildew Barnase bacterial and fungal pathogens like Botrytis and powdery mildew Glucanases bacterial and fungal pathogens like Botrytis and powdery mildew double stranded ribonuclease viruses Coat proteins viruses 17 kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. viruses a or b or viruses Nucleoprotein Pseudoubiquitin viruses Replicase viruses Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids Peroxidase lepidoptera, aphids Aminopeptidase inhibitors eg. lepidoptera, aphids Leucine aminopeptidase inhibitor Lectines lepidoptera, aphids Protease Inhibitors eg cystatin, lepidoptera, aphids patatin ribosome inactivating protein lepidoptera, aphids stilbene synthase lepidoptera, aphids, diseases HMG-CoA reductase lepidoptera, aphids Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes or general diseases CBI root knot nematodes Antifeeding principles nematodes eg root knot nematodes or root cyst nematodes

TABLE A10 crop Oil Seed rape Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy- benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides selection such as Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens oxidase antisense like Cylindrosporium, Phoma, Sclerotinia Metallothionein bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Ribonuclease bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Antifungal polypeptide AlyAFP bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia oxalate oxidase bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia glucose oxidase bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia pyrrolnitrin synthesis genes bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia serine/threonine kinases bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Cecropin B bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Phenylalanine ammonia lyase bacterial and fungal pathogens (PAL) like Cylindrosporium, Phoma, Sclerotinia Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Osmotin bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Alpha Hordothionin bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Systemin bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Polygalacturonase inhibitors bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Prf regulatory gene bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia phytoalexins bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia B-1,3-glucanase antisense bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia receptor kinase bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Hypersensitive response eliciting bacterial and fungal pathogens polypeptide like Cylindrosporium, Phoma, Sclerotinia Systemic acquires resistance viral, bacterial, fungal, nematodal (SAR) genes pathogens Chitinases bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Barnase bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia, nematodes Glucanases bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia double stranded ribonuclease viruses Coat proteins viruses 17 kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. a or b or viruses Nucleoprotein Pseudoubiquitin viruses Replicase viruses Bacillus thuringiensis toxins, lepidoptera, aphids VIP 3, Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids Peroxidase lepidoptera, aphids Aminopeptidase inhibitors eg. lepidoptera, aphids Leucine aminopeptidase inhibitor Lectines lepidoptera, aphids Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids CPTI ribosome inactivating protein lepidoptera, aphids stilbene synthase lepidoptera, aphids, diseases HMG-CoA reductase lepidoptera, aphids Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematode feeding site nematodes, root cyst nematodes

TABLE A11 Crop Brassica vegetable (cabbage, brussel sprouts, broccoli etc.) Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate Isoxazoles such as Isoxaflutol or dioxygenase (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase Diphenylethers, cyclic imides, (PROTOX) phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such selection as Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens oxidase antisense Metallothionein bacterial and fungal pathogens Ribonuclease bacterial and fungal pathogens Antifungal polypeptide AlyAFP bacterial and fungal pathogens oxalate oxidase bacterial and fungal pathogens glucose oxidase bacterial and fungal pathogens pyrrolnitrin synthesis genes bacterial and fungal pathogens serine/threonine kinases bacterial and fungal pathogens Cecropin B bacterial and fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens Osmotin bacterial and fungal pathogens Alpha Hordothionin bacterial and fungal pathogens Systemin bacterial and fungal pathogens Polygalacturonase inhibitors bacterial and fungal pathogens Prf regulatory gene bacterial and fungal pathogens phytoalexins bacterial and fungal pathogens B-1,3-glucanase antisense bacterial and fungal pathogens receptor kinase bacterial and fungal pathogens Hypersensitive response eliciting bacterial and fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases bacterial and fungal pathogens Barnase bacterial and fungal pathogens Glucanases bacterial and fungal pathogens double stranded ribonuclease viruses Coat proteins viruses 17 kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. viruses a or b or Nucleoprotein Pseudoubiquitin viruses Replicase viruses Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids Peroxidase lepidoptera, aphids Aminopeptidase inhibitors eg. lepidoptera, aphids Leucine aminopeptidase inhibitor Lectines lepidoptera, aphids Protease Inhibitors eg cystatin, lepidoptera, aphids patatin, CPTI ribosome inactivating protein lepidoptera, aphids stilbene synthase lepidoptera, aphids, diseases HMG-CoA reductase lepidoptera, aphids Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematode feeding site nematodes, root cyst nematodes

TABLE A12 Crop Pome fruits eg apples, pears Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like apple oxidase antisense scab or fireblight Metallothionein bacterial and fungal pathogens like apple scab or fireblight Ribonuclease bacterial and fungal pathogens like apple scab or fireblight Antifungal polypeptide AlyAFP bacterial and fungal pathogens like apple scab or fireblight oxalate oxidase bacterial and fungal pathogens like apple scab or fireblight glucose oxidase bacterial and fungal pathogens like apple scab or fireblight pyrrolnitrin synthesis genes bacterial and fungal pathogens like apple scab or fireblight serine/threonine kinases bacterial and fungal pathogens like apple scab or fireblight Cecropin B bacterial and fungal pathogens like apple scab or fireblight Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens like apple scab or fireblight Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like apple scab or fireblight Osmotin bacterial and fungal pathogens like apple scab or fireblight Alpha Hordothionin bacterial and fungal pathogens like apple scab or fireblight Systemin bacterial and fungal pathogens like apple scab or fireblight Polygalacturonase inhibitors bacterial and fungal pathogens like apple scab or fireblight Prf regulatory gene bacterial and fungal pathogens like apple scab or fireblight phytoalexins bacterial and fungal pathogens like apple scab or fireblight B-1,3-glucanase antisense bacterial and fungal pathogens like apple scab or fireblight receptor kinase bacterial and fungal pathogens like apple scab or fireblight Hypersensitive response eliciting bacterial and fungal pathogens like apple polypeptide scab or fireblight Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial and fungal pathogens like apple scab or fireblight Lysozym bacterial and fungal pathogens like apple scab or fireblight Chitinases bacterial and fungal pathogens like apple scab or fireblight Barnase bacterial and fungal pathogens like apple scab or fireblight Glucanases bacterial and fungal pathogens like apple scab or fireblight double stranded ribonuclease viruses Coat proteins viruses 17 kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. a or b or viruses Nucleoprotein Pseudoubiquitin viruses Replicase viruses Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids, mites Peroxidase lepidoptera, aphids, mites Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites aminopeptidase inhibitor Lectines lepidoptera, aphids, mites Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites CPTI ribosome inactivating protein lepidoptera, aphids, mites stilbene synthase lepidoptera, aphids, diseases, mites HMG-CoA reductase lepidoptera, aphids, mites Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes

TABLE A13 Crop Melons Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and Ioxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens like oxidase antisense phytophtora Metallothionein bacterial or fungal pathogens like phytophtora Ribonuclease bacterial or fungal pathogens like phytophtora Antifungal polypeptide AlyAFP bacterial or fungal pathogens like phytophtora oxalate oxidase bacterial or fungal pathogens like phytophtora glucose oxidase bacterial or fungal pathogens like phytophtora pyrrolnitrin synthesis genes bacterial or fungal pathogens like phytophtora serine/threonine kinases bacterial or fungal pathogens like phytophtora Cecropin B bacterial or fungal pathogens like phytophtora Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens like phytophtora Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens like phytophtora Osmotin bacterial or fungal pathogens like phytophtora Alpha Hordothionin bacterial or fungal pathogens like phytophtora Systemin bacterial or fungal pathogens like phytophtora Polygalacturonase inhibitors bacterial or fungal pathogens like phytophtora Prf regulatory gene bacterial or fungal pathogens like phytophtora phytoalexins bacterial or fungal pathogens like phytophtora B-1,3-glucanase antisense bacterial or fungal pathogens like phytophtora receptor kinase bacterial or fungal pathogens like phytophtora Hypersensitive response eliciting bacterial or fungal pathogens like polypeptide phytophtora Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens like phytophtora Lysozym bacterial or fungal pathogens like phytophtora Chitinases bacterial or fungal pathogens like phytophtora Barnase bacterial or fungal pathogens like phytophtora Glucanases bacterial or fungal pathogens like phytophtora double stranded ribonuclease viruses as CMV,, PRSV, WMV2, SMV, ZYMV Coat proteins viruses as CMV,, PRSV, WMV2, SMV, ZYMV 17 kDa or 60 kDa protein viruses as CMV,, PRSV, WMV2, SMV, ZYMV Nuclear inclusion proteins eg. a or b or viruses as CMV,, PRSV, WMV2, SMV, Nucleoprotein ZYMV Pseudoubiquitin viruses as CMV,, PRSV, WMV2, SMV, ZYMV Replicase viruses as CMV,, PRSV, WMV2, SMV, ZYMV Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids, mites, whitefly Peroxidase lepidoptera, aphids, mites, whitefly Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, whitefly aminopeptidase inhibitor Lectines lepidoptera, aphids, mites, whitefly Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, whitefly CPTI, virgiferin ribosome inactivating protein lepidoptera, aphids, mites, whitefly stilbene synthase lepidoptera, aphids, mites, whitefly HMG-CoA reductase lepidoptera, aphids, mites, whitefly Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes

TABLE A14 Crop Banana Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens Chitinases bacterial or fungal pathogens Barnase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as Banana bunchy top virus (BBTV) Coat proteins viruses as Banana bunchy top virus (BBTV) 17 kDa or 60 kDa protein viruses as Banana bunchy top virus (BBTV) Nuclear inclusion proteins eg. a or b or viruses as Banana bunchy top virus Nucleoprotein (BBTV) Pseudoubiquitin viruses as Banana bunchy top virus (BBTV) Replicase viruses as Banana bunchy top virus (BBTV) Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes Peroxidase lepidoptera, aphids, mites, nematodes Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes aminopeptidase inhibitor Lectines lepidoptera, aphids, mites, nematodes Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes CPTI, virgiferin ribosome inactivating protein lepidoptera, aphids, mites, nematodes stilbene synthase lepidoptera, aphids, mites, nematodes HMG-CoA reductase lepidoptera, aphids, mites, nematodes Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes

TABLE A15 Crop Cotton Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and Ioxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens Chitinases bacterial or fungal pathogens Barnase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as wound tumor virus (WTV) Coat proteins viruses as wound tumor virus (WTV) 17 kDa or 60 kDa protein viruses as wound tumor virus (WTV) Nuclear inclusion proteins eg. a or b or viruses as wound tumor virus (WTV) Nucleoprotein Pseudoubiquitin viruses as wound tumor virus (WTV) Replicase viruses as wound tumor virus (WTV) Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefly Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes, whitefly Peroxidase lepidoptera, aphids, mites, nematodes, whitefly Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly Lectines lepidoptera, aphids, mites, nematodes, whitefly Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly ribosome inactivating protein lepidoptera, aphids, mites, nematodes, whitefly stilbene synthase lepidoptera, aphids, mites, nematodes, whitefly HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes

TABLE A16 Crop Sugarcane Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and Ioxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens eg clavibacter Chitinases bacterial or fungal pathogens Barnase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as SCMV, SrMV Coat proteins viruses as SCMV, SrMV 17 kDa or 60 kDa protein viruses as SCMV, SrMV Nuclear inclusion proteins eg. a or b or viruses as SCMV, SrMV Nucleoprotein Pseudoubiquitin viruses as SCMV, SrMV Replicase viruses as SCMV, SrMV Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefly, beetles eg mexican rice borer Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer Peroxidase lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beetles eg mexican rice borer Lectines lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles eg mexican rice borer ribosome inactivating protein lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer stilbene synthase lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes

TABLE A17 Crop Sunflower Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens eg sclerotinia glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens Chitinases bacterial or fungal pathogens Barnase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as CMV, TMV Coat proteins viruses as CMV, TMV 17 kDa or 60 kDa protein viruses as CMV, TMV Nuclear inclusion proteins eg. a or b or viruses as CMV, TMV Nucleoprotein Pseudoubiquitin viruses as CMV, TMV Replicase viruses as CMV, TMV Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefly, beetles Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes, whitefly, beetles Peroxidase lepidoptera, aphids, mites, nematodes, whitefly, beetles Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beetles Lectines lepidoptera, aphids, mites, nematodes, whitefly, beetles Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles ribosome inactivating protein lepidoptera, aphids, mites, nematodes, whitefly, beetles stilbene synthase lepidoptera, aphids, mites, nematodes, whitefly, beetles HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly, beetles Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes

TABLE A18 Crop Sugarbeet, Beet root Effected target or expressed principle(s) Crop phenotype/Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc. Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens eg sclerotinia glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens AX + WIN proteins bacterial or fungal pathogens like Cercospora beticola receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens Chitinases bacterial or fungal pathogens Barnase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as BNYVV Coat proteins viruses as BNYVV 17 kDa or 60 kDa protein viruses as BNYVV Nuclear inclusion proteins eg. a or b or viruses as BNYVV Nucleoprotein Pseudoubiquitin viruses as BNYVV Replicase viruses as BNYVV Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefly, beetles, rootflies Xenorhabdus toxins 3-Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies Peroxidase lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beetles, rootflies Lectines lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles, rootflies ribosome inactivating protein lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies stilbene synthase lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies Cyst nematode hatching stimulus cyst nematodes Barnase nematodes eg root knot nematodes and cyst nematodes Beet cyst nematode resistance locus cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes

The abovementioned animal pests which can be controlled by the method according to the invention (A) include, for example, insects, representatives of the order acarina and representatives of the class nematoda; especially

from the order Lepidoptera Acleris spp., Adoxophyes spp., especially Adoxophyes reticulana; Aegeria spp., Agrotis spp., especially Agrotis spinifera; Alabama argillaceae, Amylois spp., Anticarsia gemmatalis, Archips spp., Argyrotaenia spp., Autographa spp., Busseola fusca, Cadra cautella, Carposina nipponensis, Chilo spp., Choristoneura spp., Clysia ambiguella, Cnaphalocrocis spp., Cnephasia spp., Cochylis spp., Coleophora spp., Crocidolomia binotalis, Cryptophlebia leucotreta, Cydia spp., especially Cydia pomonella; Diatraea spp., Diparopsis castanea, Earias spp., Ephestia spp., especially E. Khüniella; Eucosma spp., Eupoecilia ambiguella, Euproctis spp., Euxoa spp., Grapholita spp., Hedya nubiferana, Heliothis spp., especially H. virescens and H. zea; Hellula undalis, Hyphantria cunea, Keiferia lycopersicella, Leucoptera scitella, Lithocollethis spp., Lobesia spp., Lymantria spp., Lyonetia spp., Malacosoma spp., Mamestra brassicae, Manduca sexta, Operophtera spp., Ostrinia nubilalis, Pammene spp., Pandemis spp., Panolis flammea, Pectinophora spp., Phthorimaea operculella, Pieris rapae, Pieris spp., Plutella xylostella, Prays spp., Scirpophaga spp., Sesamia spp., Sparganothis spp., Spodopteralittoralis, Synanthedon spp., Thaumetopoea spp., Tortrix spp., Trichoplusia ni and Yponomeuta spp.; from the order Coleoptera, for example Agriotes spp., Anthonomus spp., Atomaria linearis, Chaetocnema tibialis, Cosmopolites spp., Curculio spp., Dermestes spp., Diabrotica spp., Epilachna spp., Eremnus spp., Leptinotarsa decemlineata, Lissorhoptrus spp., Melolontha spp., Oryzaephilus spp., Otiorhynchus spp., Phlyctinus spp., Popillia spp., Psylliodes spp., Rhizopertha spp., Scarabeidae, Sitophilus spp., Sitotroga spp., Tenebrio spp., Tribolium spp. and Trogoderma spp.; from the order Orthoptera, for example Blatta spp., Blattella spp., Gryllotalpa spp., Leucophaea maderae, Locusta spp., Periplaneta spp. and Schistocerca spp.; from the order Isoptera, for example Reticulitermes spp.; from the order Psocoptera, for example Liposcelis spp.; from the order Anoplura, for example Haematopinus spp., Linognathus spp., Pediculus spp., Pemphigus spp. and Phylloxera spp.; from the order Mallophaga, for example Damalinea spp. and Trichodectes spp.; from the order Thysanoptera, for example Frankliniella spp., Hercinothrips spp., Taeniothrips spp., Thrips palmi, Thrips tabaci and Scirtothrips aurantii; from the order Heteroptera, for example Cimex spp., Distantiella theobroma, Dysdercus spp., Euchistus spp. Eurygaster spp. Leptocorisa spp., Nezara spp., Piesma spp., Rhodnius spp., Sahlbergella singularis, Scotinophara spp. and Triatoma spp.; from the order Homoptera, for example Aleurothrixus floccosus, Aleyrodes brassicae, Aonidiella aurantii, Aphididae, Aphiscraccivora, A. fabae, A. gosypii; Aspidiotus spp., Bemisia tabaci, Ceroplaster spp., Chrysomphalus aonidium, Chrysomphalus dictyospermi, Coccus hesperidum, Empoasca spp., Eriosoma lanigerum, Erythroneura spp., Gascardia spp., Laodelphax spp., Lecanium corni, Lepidosaphes spp., Macrosiphus spp., Myzus spp., especially M. persicae; Nephotettix spp., especially N. cincticeps; Nilaparvata spp., especially N. lugens; Paratoria spp., Pemphigus spp., Planococcus spp., Pseudaulacaspis spp., Pseudococcus spp., especially P. Fragilis, P. citriculus and P. comstocki; Psylla spp., especially P. pyri; Pulvinaria aethiopica, Quadraspidiotus spp., Rhopalosiphum spp., Saissetia spp., Scaphoideus spp., Schizaphis spp., Sitobion spp., Trialeurodes vaporariorum, Trioza erytreae and Unaspis citri; from the order Hymenoptera, for example Acromyrmex, Atta spp., Cephus spp., Diprion spp., Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium pharaonis, Neodiprion spp., Solenopsis spp. and Vespa spp.; from the order Diptera, for example Aedes spp., Antherigona soccata, Bibio hortulanus, Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp., Cuterebra spp., Dacus spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Glossina spp., Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza spp., Musca spp., Oestrus spp., Orseolia spp., Oscinella frit, Pegomyia hyoscyami, Phorbia spp., Rhagoletis pomonella, Sciara spp., Stomoxys spp., Tabanus spp., Tannia spp. and Tipula spp.; from the order Siphonaptera, for example Ceratophyllus spp. and Xenopsylla cheopis; from the order Thysanura, for example Lepisma saccharina and from the order Acarina, for example Acarus siro, Aceria sheldoni; Aculus spp., especially A. schlechtendali; Amblyomma spp., Argas spp., Boophilus spp., Brevipalpus spp., especially B. californicus and B. phoenicis; Bryobia praetiosa, Calipitrimerus spp., Chorioptes spp., Dermanyssus gallinae, Eotetranychus spp., especially E. carpini and E. orientalis; Eriophyes spp., especially E. vitis; Hyalomma spp., Ixodes spp., Olygonychus pratensis, Ornithodoros spp., Panonychus spp., especially P. ulmi and P. citri; Phyllocoptruta spp., especially P. oleivora; Polyphagotarsonemus spp., especially P. latus; Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptes spp., Tarsonemus spp. and Tetranychus spp., in particular T. urticae, T. cinnabarinus and T. Kanzawai; representatives of the class Nematoda; (1) nematodes selected from the group consisting of root knot nematodes, cyst-forming nematodes, stem eelworms and foliar nematodes; (2) nematodes selected from the group consisting of Anguina spp.; Aphelenchoides spp.; Ditylenchus spp.; Globodera spp., for example Globodera rostochiensis; Heterodera spp., for example Heterodera avenae, Heterodera glycines, Heterodera schachtii or Heterodera trifolii; Longidorus spp.; Meloidogyne spp., for example Meloidogyne incognita or Meloidogyne javanica; Pratylenchus, for example Pratylenchus neglectans or Pratylenchus penetrans; Radopholus spp., for example Radopholus similis; Trichodorus spp.; Tylenchulus, for example Tylenchulus semipenetrans; and Xiphinema spp.; or (3) nematodes selected from the group consisting of Heterodera spp., for example Heterodera glycines; and Meloidogyne spp., for example Meloidogyne incognita.

The method according to the invention (A) allows pests of the abovementioned type to be controlled, i.e. contained or destroyed, which occur, in particular, on transgenic plants, mainly useful plants and ornamentals in agriculture, in horticulture and in forests, or on parts, such as fruits, flowers, foliage, stalks, tubers or roots, of such plants, the protection against these pests in some cases even extending to plant parts which form at a later point in time.

The method according to the invention (A) can be employed advantageously for controlling pests in rice, cereals such as maize or sorghum; in fruit, for example stone fruit, pome fruit and soft fruit such as apples, pears, plums, peaches, almonds, cherries or berries, for example strawberries, raspberries and blackberries; in legumes such as beans, lentils, peas or soya beans; in oil crops such as oilseed rape, mustard, poppies, olives, sunflowers, coconuts, castor-oil plants, cacao or peanuts; in the marrow family such as pumpkins, cucumbers or melons; in fibre plants such as cotton, flax, hemp or jute; in citrus fruit such as oranges, lemons, grapefruit or tangerines; in vegetables such as spinach, lettuce, asparagus, cabbage species, carrots, onions, tomatoes, potatoes, beet or capsicum; in the laurel family such as avocado, Cinnamonium or camphor; or in tobacco, nuts, coffee, egg plants, sugar cane, tea, pepper, grapevines, hops, the banana family, latex plants or ornamentals, mainly in maize, rice, cereals, soya beans, tomatoes, cotton, potatoes, sugar beet, rice and mustard; in particular in cotton, rice, soya beans, potatoes and maize.

It has emerged that the method according to the invention (A) is valuable preventatively and/or curatively in the field of pest control even at low use concentrations of the pesticidal composition and that a very favourable biocidal spectrum is achieved thereby. Combined with a favourable compatibility of the composition employed with warm-blooded species, fish and plants, the method according to the invention can be employed against all or individual developmental stages of normally-sensitive, but also of normally-resistant, animal pests such as insects and representatives of the order Acarina, depending on the species of the transgenic crop plant to be protected from attack by pests. The insecticidal and/or acaricidal effect of the method according to the invention may become apparent directly, i.e. in a destruction of the pests which occurs immediately or only after some time has elapsed, for example, during ecdysis, or indirectly, for example as a reduced oviposition and/or hatching rate, the good action corresponding to a destruction rate (mortality) of at least 40 to 50%.

Depending on the intended aims and the prevailing circumstances, the pesticides within the scope of invention (A), which are known per se, are emulsifiable concentrates, suspension concentrates, directly sprayable or dilutable solutions, spreadable pastes, dilute emulsions, wettable powders, soluble powders, dispersible powders, wettable powders, dusts, granules or encapsulations in polymeric substances which comprise a macrolide compound.

The active ingredients are employed in these compositions together with at least one of the auxiliaries conventionally used in art of formulation, such as extenders, for example solvents or solid carriers, or such as surface-active compounds (surfactants).

Formulation auxiliaries which are used are, for example, solid carriers, solvents, stabilizers, “slow release” auxiliaries, colourants and, if appropriate, surface-active substances (surfactants). Suitable carriers and auxiliaries are all those substances which are conventionally used for crop protection products. Suitable auxiliaries such as solvents, solid carriers, surface-active compounds, non-ionic surfactants, cationic surfactants, anionic surfactants and other auxiliaries in the compositions employed according to the invention are, for example, those which have been described in EP-A-736 252.

These compositions for controlling pests can be formulated, for example, as wettable powders, dusts, granules, solutions, emulsifiable concentrates, emulsions, suspension concentrates or aerosols. For example, the compositions are of the type described in EP-A-736 252.

The action of the compositions within the scope of invention (A) which comprise a macrolide compound can be extended substantially and adapted to prevailing circumstances by adding other insecticidally, acaricidally and/or fungicidally active ingredients. Suitable examples of added active ingredients are representatives of the following classes of active ingredients: organophosphorous compounds, nitrophenols and derivatives, formamidines, ureas, carbamates, pyrethroids, chlorinated hydrocarbons; especially preferred components in mixtures are, for example, thiamethoxam, pymetrozine, fenoxycarb, imidacloprid, Ti-435, fipronil, pyriproxyfen, emamectin, diazinon or diafenthiuron.

As a rule, the compositions within the scope of invention (A) comprise 0.1 to 99%, in particular 0.1 to 95%, of a macrolide compound and 1 to 99.9%, in particular 5 to 99.9%, of—at least—one solid or liquid auxiliary, it being possible, as a rule, for 0 to 25%, in particular 0.1 to 20%, of the compositions to be surfactants (% in each case meaning percent by weight). While concentrated compositions are more preferred as commercial products, the end user will, as a rule, use dilute compositions which have considerably lower concentrations of active ingredient.

The compositions according to the invention (A) may also comprise other solid or liquid auxiliaries, such as stabilisers, for example epoxidized or unepoxidized vegetable oils (for example epoxidized coconut oil, rapeseed oil or soya bean oil), antifoams, for example silicone oil, preservatives, viscosity regulators, binders and/or tackifiers, and also fertilizers or other active ingredients for achieving specific effects, for example, bactericides, fungicides, nematicides, molluscicides or herbicides.

The compositions according to the invention (A) are produced in a known manner, for example prior to mixing with the auxiliary/auxiliaries by grinding, screening and/or compressing the active ingredient, for example to give a particular particle size, and by intimately mixing and/or grinding the active ingredient with the auxiliary/auxiliaries.

The method according to the invention for controlling pests of the abovementioned type is carried out in a manner known per se to those skilled in the art, depending on the intended aims and prevailing circumstances, that is to say by spraying, wetting, atomizing, dusting, brushing on, seed dressing, scattering or pouring of the composition. Typical use concentrations are between 0.1 and 1000 ppm, preferably between 0.1 and 500 ppm of active ingredient. The application rate may vary within wide ranges and depends on the soil constitution, the type of application (foliar application; seed dressing; application in the seed furrow), the transgenic crop plant, the pest to be controlled, the climatic circumstances prevailing in each case, and other factors determined by the type of application, timing of application and target crop. The application rates per hectare are generally 1 to 2000 g of macrolide compound per hectare, in particular 10 to 1000 g/ha, preferably 10 to 500 g/ha, especially preferably 10 to 200 g/ha.

A preferred type of application in the field of crop protection within the scope of invention (A) is application to the foliage of the plants (foliar application), it being possible to adapt frequency and rate of application to the risk of infestation with the pest in question. However, the active ingredient may also enter into the plants via the root system (systemic action), by drenching the site of the plants with a liquid composition or by incorporating the active ingredient in solid form into the site of the plants, for example into the soil, for example in the form of granules (soil application). In the case of paddy rice crops, such granules may be metered into the flooded paddy field.

The compositions according to invention (A) are also suitable for protecting propagation material of transgenic plants, for example seed, such as fruits, tubers or kernels, or plant cuttings, from animal pests, in particular insects and representatives of the order Acarina. The propagation material can be treated with the composition prior to application, for example, seed being dressed prior to sowing. The active ingredient may also be applied to seed kernels (coating), either by soaking the kernels in a liquid composition or by coating them with a solid composition. The composition may also be applied to the site of application when applying the propagation material, for example into the seed furrow during sowing. These treatment methods for plant propagation material and the plant propagation material treated thus are a further subject of the invention.

Examples of formulations of macrolide compounds which can be used in the method according to the invention (A), for instance solutions, granules, dusts, sprayable powders, emulsion concentrates, coated granules and suspension concentrates, are of the type as has been described in, for example, EP-A-580 553, Examples F1 to F10.

TABLE B AP Control of B.1 CryIA(a) Adoxophyes spp. B.2 CryIA(a) Agrotis spp. B.3 CryIA(a) Alabama argillaceae B.4 CryIA(a) Anticarsia gemmatalis B.5 CryIA(a) Chilo spp. B.6 CryIA(a) Clysia ambiguella B.7 CryIA(a) Crocidolomia binotalis B.8 CryIA(a) Cydia spp. B.9 CryIA(a) Diparopsis castanea B.10 CryIA(a) Earias spp. B.11 CryIA(a) Ephestia spp. B.12 CryIA(a) Heliothis spp. B.13 CryIA(a) Hellula undalis B.14 CryIA(a) Keiferia lycopersicella B.15 CryIA(a) Leucoptera scitella B.16 CryIA(a) Lithocollethis spp. B.17 CryIA(a) Lobesia botrana B.18 CryIA(a) Ostrinia nubilalis B.19 CryIA(a) Pandemis spp. B.20 CryIA(a) Pectinophora gossyp. B.21 CryIA(a) Phyllocnistis citrella B.22 CryIA(a) Pieris spp. B.23 CryIA(a) Plutella xylostella B.24 CryIA(a) Scirpophaga spp. B.25 CryIA(a) Sesamia spp. B.26 CryIA(a) Sparganothis spp. B.27 CryIA(a) Spodoptera spp. B.28 CryIA(a) Tortrix spp. B.29 CryIA(a) Trichoplusia ni B.30 CryIA(a) Agriotes spp. B.31 CryIA(a) Anthonomus grandis B.32 CryIA(a) Curculio spp. B.33 CryIA(a) Diabrotica balteata B.34 CryIA(a) Leptinotarsa spp. B.35 CryIA(a) Lissorhoptrus spp. B.36 CryIA(a) Otiorhynchus spp. B.37 CryIA(a) Aleurothrixus spp. B.38 CryIA(a) Aleyrodes spp. B.39 CryIA(a) Aonidiella spp. B.40 CryIA(a) Aphididae spp. B.41 CryIA(a) Aphis spp. B.42 CryIA(a) Bemisia tabaci B.43 CryIA(a) Empoasca spp. B.44 CryIA(a) Mycus spp. B.45 CryIA(a) Nephotettix spp. B.46 CryIA(a) Nilaparvata spp. B.47 CryIA(a) Pseudococcus spp. B.48 CryIA(a) Psylla spp. B.49 CryIA(a) Quadraspidiotus spp. B.50 CryIA(a) Schizaphis spp. B.51 CryIA(a) Trialeurodes spp. B.52 CryIA(a) Lyriomyza spp. B.53 CryIA(a) Oscinella spp. B.54 CryIA(a) Phorbia spp. B.55 CryIA(a) Frankliniella spp. B.56 CryIA(a) Thrips spp. B.57 CryIA(a) Scirtothrips aurantii B.58 CryIA(a) Aceria spp. B.59 CryIA(a) Aculus spp. B.60 CryIA(a) Brevipalpus spp. B.61 CryIA(a) Panonychus spp. B.62 CryIA(a) Phyllocoptruta spp. B.63 CryIA(a) Tetranychus spp. B.64 CryIA(a) Heterodera spp. B.65 CryIA(a) Meloidogyne spp. B.66 CryIA(b) Adoxophyes spp. B.67 CryIA(b) Agrotis spp. B.68 CryIA(b) Alabama argillaceae B.69 CryIA(b) Anticarsia gemmatalis B.70 CryIA(b) Chilo spp. B.71 CryIA(b) Clysia ambiguella B.72 CryIA(b) Crocidolomia binotalis B.73 CryIA(b) Cydia spp. B.74 CryIA(b) Diparopsis castanea B.75 CryIA(b) Earias spp. B.76 CryIA(b) Ephestia spp. B.77 CryIA(b) Heliothis spp. B.78 CryIA(b) Hellula undalis B.79 CryIA(b) Keiferia lycopersicella B.80 CryIA(b) Leucoptera scitella B.81 CryIA(b) Lithocollethis spp. B.82 CryIA(b) Lobesia botrana B.83 CryIA(b) Ostrinia nubilalis B.84 CryIA(b) Pandemis spp. B.85 CryIA(b) Pectinophora gossyp. B.86 CryIA(b) Phyllocnistis citrella B.87 CryIA(b) Pieris spp. B.88 CryIA(b) Plutella xylostella B.89 CryIA(b) Scirpophaga spp. B.90 CryIA(b) Sesamia spp. B.91 CryIA(b) Sparganothis spp. B.92 CryIA(b) Spodoptera spp. B.93 CryIA(b) Tortrix spp. B.94 CryIA(b) Trichoplusia ni B.95 CryIA(b) Agriotes spp. B.96 CryIA(b) Anthonomus grandis B.97 CryIA(b) Curculio spp. B.98 CryIA(b) Diabrotica balteata B.99 CryIA(b) Leptinotarsa spp. B.100 CryIA(b) Lissorhoptrus spp. B.101 CryIA(b) Otiorhynchus spp. B.102 CryIA(b) Aleurothrixus spp. B.103 CryIA(b) Aleyrodes spp. B.104 CryIA(b) Aonidiella spp. B.105 CryIA(b) Aphididae spp. B.106 CryIA(b) Aphis spp. B.107 CryIA(b) Bemisia tabaci B.108 CryIA(b) Empoasca spp. B.109 CryIA(b) Mycus spp. B.110 CryIA(b) Nephotettix spp. B.111 CryIA(b) Nilaparvata spp. B.112 CryIA(b) Pseudococcus spp. B.113 CryIA(b) Psylla spp. B.114 CryIA(b) Quadraspidiotus spp. B.115 CryIA(b) Schizaphis spp. B.116 CryIA(b) Trialeurodes spp. B.117 CryIA(b) Lyriomyza spp. B.118 CryIA(b) Oscinella spp. B.119 CryIA(b) Phorbia spp. B.120 CryIA(b) Frankliniella spp. B.121 CryIA(b) Thrips spp. B.122 CryIA(b) Scirtothrips aurantii B.123 CryIA(b) Aceria spp. B.124 CryIA(b) Aculus spp. B.125 CryIA(b) Brevipalpus spp. B.126 CryIA(b) Panonychus spp. B.127 CryIA(b) Phyllocoptruta spp. B.128 CryIA(b) Tetranychus spp. B.129 CryIA(b) Heterodera spp. B.130 CryIA(b) Meloidogyne spp. B.131 CryIA(c) Adoxophyes spp. B.132 CryIA(c) Agrotis spp. B.133 CryIA(c) Alabama argillaceae B.134 CryIA(c) Anticarsia gemmatalis B.135 CryIA(c) Chilo spp. B.136 CryIA(c) Clysia ambiguella B.137 CryIA(c) Crocidolomia binotalis B.138 CryIA(c) Cydia spp. B.139 CryIA(c) Diparopsis castanea B.140 CryIA(c) Earias spp. B.141 CryIA(c) Ephestia spp. B.142 CryIA(c) Heliothis spp. B.143 CryIA(c) Hellula undalis B.144 CryIA(c) Keiferia lycopersicella B.145 CryIA(c) Leucoptera scitella B.146 CryIA(c) Lithocollethis spp. B.147 CryIA(c) Lobesia botrana B.148 CryIA(c) Ostrinia nubilalis B.149 CryIA(c) Pandemis spp. B.150 CryIA(c) Pectinophora gossypiella. B.151 CryIA(c) Phyllocnistis citrella B.152 CryIA(c) Pieris spp. B.153 CryIA(c) Plutella xylostella B.154 CryIA(c) Scirpophaga spp. B.155 CryIA(c) Sesamia spp. B.156 CryIA(c) Sparganothis spp. B.157 CryIA(c) Spodoptera spp. B.158 CryIA(c) Tortrix spp. B.159 CryIA(c) Trichoplusia ni B.160 CryIA(c) Agriotes spp. B.161 CryIA(c) Anthonomus grandis B.162 CryIA(c) Curculio spp. B.163 CryIA(c) Diabrotica balteata B.164 CryIA(c) Leptinotarsa spp. B.165 CryIA(c) Lissorhoptrus spp. B.166 CryIA(c) Otiorhynchus spp. B.167 CryIA(c) Aleurothrixus spp. B.168 CryIA(c) Aleyrodes spp. B.169 CryIA(c) Aonidiella spp. B.170 CryIA(c) Aphididae spp. B.171 CryIA(c) Aphis spp. B.172 CryIA(c) Bemisia tabaci B.173 CryIA(c) Empoasca spp. B.174 CryIA(c) Mycus spp. B.175 CryIA(c) Nephotettix spp. B.176 CryIA(c) Nilaparvata spp. B.177 CryIA(c) Pseudococcus spp. B.178 CryIA(c) Psylla spp. B.179 CryIA(c) Quadraspidiotus spp. B.180 CryIA(c) Schizaphis spp. B.181 CryIA(c) Trialeurodes spp. B.182 CryIA(c) Lyriomyza spp. B.183 CryIA(c) Oscinella spp. B.184 CryIA(c) Phorbia spp. B.185 CryIA(c) Frankliniella spp. B.186 CryIA(c) Thrips spp. B.187 CryIA(c) Scirtothrips aurantii B.188 CryIA(c) Aceria spp. B.189 CryIA(c) Aculus spp. B.190 CryIA(c) Brevipalpus spp. B.191 CryIA(c) Panonychus spp. B.192 CryIA(c) Phyllocoptruta spp. B.193 CryIA(c) Tetranychus spp. B.194 CryIA(c) Heterodera spp. B.195 CryIA(c) Meloidogyne spp. B.196 CryIIA Adoxophyes spp. B.197 CryIIA Agrotis spp. B.198 CryIIA Alabama argillaceae B.199 CryIIA Anticarsia gemmatalis B.200 CryIIA Chilo spp. B.201 CryIIA Clysia ambiguella B.202 CryIIA Crocidolomia binotalis B.203 CryIIA Cydia spp. B.204 CryIIA Diparopsis castanea B.205 CryIIA Earias spp. B.206 CryIIA Ephestia spp. B.207 CryIIA Heliothis spp. B.208 CryIIA Hellula undalis B.209 CryIIA Keiferia lycopersicella B.210 CryIIA Leucoptera scitella B.211 CryIIA Lithocollethis spp. B.212 CryIIA Lobesia botrana B.213 CryIIA Ostrinia nubilalis B.214 CryIIA Pandemis spp. B.215 CryIIA Pectinophora gossyp. B.216 CryIIA Phyllocnistis citrella B.217 CryIIA Pieris spp. B.218 CryIIA Plutella xylostella B.219 CryIIA Scirpophaga spp. B.220 CryIIA Sesamia spp. B.221 CryIIA Sparganothis spp. B.222 CryIIA Spodoptera spp. B.223 CryIIA Tortrix spp. B.224 CryIIA Trichoplusia ni B.225 CryIIA Agriotes spp. B.226 CryIIA Anthonomus grandis B.227 CryIIA Curculio spp. B.228 CryIIA Diabrotica balteata B.229 CryIIA Leptinotarsa spp. B.230 CryIIA Lissorhoptrus spp. B.231 CryIIA Otiorhynchus spp. B.232 CryIIA Aleurothrixus spp. B.233 CryIIA Aleyrodes spp. B.234 CryIIA Aonidiella spp. B.235 CryIIA Aphididae spp. B.236 CryIIA Aphis spp. B.237 CryIIA Bemisia tabaci B.238 CryIIA Empoasca spp. B.239 CryIIA Mycus spp. B.240 CryIIA Nephotettix spp. B.241 CryIIA Nilaparvata spp. B.242 CryIIA Pseudococcus spp. B.243 CryIIA Psylla spp. B.244 CryIIA Quadraspidiotus spp. B.245 CryIIA Schizaphis spp. B.246 CryIIA Trialeurodes spp. B.247 CryIIA Lyriomyza spp. B.248 CryIIA Oscinella spp. B.249 CryIIA Phorbia spp. B.250 CryIIA Frankliniella spp. B.251 CryIIA Thrips spp. B.252 CryIIA Scirtothrips aurantii B.253 CryIIA Aceria spp. B.254 CryIIA Aculus spp. B.255 CryIIA Brevipalpus spp. B.256 CryIIA Panonychus spp. B.257 CryIIA Phyllocoptruta spp. B.258 CryIIA Tetranychus spp. B.259 CryIIA Heterodera spp. B.260 CryIIA Meloidogyne spp. B.261 CryIIIA Adoxophyes spp. B.262 CryIIIA Agrotis spp. B.263 CryIIIA Alabama argillaceae B.264 CryIIIA Anticarsia gemmatalis B.265 CryIIIA Chilo spp. B.266 CryIIIA Clysia ambiguella B.267 CryIIIA Crocidolomia binotalis B.268 CryIIIA Cydia spp. B.269 CryIIIA Diparopsis castanea B.270 CryIIIA Earias spp. B.271 CryIIIA Ephestia spp. B.272 CryIIIA Heliothis spp. B.273 CryIIIA Hellula undalis B.274 CryIIIA Keiferia lycopersicella B.275 CryIIIA Leucoptera scitella B.276 CryIIIA Lithocollethis spp. B.277 CryIIIA Lobesia botrana B.278 CryIIIA Ostrinia nubilalis B.279 CryIIIA Pandemis spp. B.280 CryIIIA Pectinophora gossyp. B.281 CryIIIA Phyllocnistis citrella B.282 CryIIIA Pieris spp. B.283 CryIIIA Plutella xylostella B.284 CryIIIA Scirpophaga spp. B.285 CryIIIA Sesamia spp. B.286 CryIIIA Sparganothis spp. B.287 CryIIIA Spodoptera spp. B.288 CryIIIA Tortrix spp. B.289 CryIIIA Trichoplusia ni B.290 CryIIIA Agriotes spp. B.291 CryIIIA Anthonomus grandis B.292 CryIIIA Curculio spp. B.293 CryIIIA Diabrotica balteata B.294 CryIIIA Leptinotarsa spp. B.295 CryIIIA Lissorhoptrus spp. B.296 CryIIIA Otiorhynchus spp. B.297 CryIIIA Aleurothrixus spp. B.298 CryIIIA Aleyrodes spp. B.299 CryIIIA Aonidiella spp. B.300 CryIIIA Aphididae spp. B.301 CryIIIA Aphis spp. B.302 CryIIIA Bemisia tabaci B.303 CryIIIA Empoasca spp. B.304 CryIIIA Mycus spp. B.305 CryIIIA Nephotettix spp. B.306 CryIIIA Nilaparvata spp. B.307 CryIIIA Pseudococcus spp. B.308 CryIIIA Psylla spp. B.309 CryIIIA Quadraspidiotus spp. B.310 CryIIIA Schizaphis spp. B.311 CryIIIA Trialeurodes spp. B.312 CryIIIA Lyriomyza spp. B.313 CryIIIA Oscinella spp. B.314 CryIIIA Phorbia spp. B.315 CryIIIA Frankliniella spp. B.316 CryIIIA Thrips spp. B.317 CryIIIA Scirtothrips aurantii B.318 CryIIIA Aceria spp. B.319 CryIIIA Aculus spp. B.320 CryIIIA Brevipalpus spp. B.321 CryIIIA Panonychus spp. B.322 CryIIIA Phyllocoptruta spp. B.323 CryIIIA Tetranychus spp. B.324 CryIIIA Heterodera spp. B.325 CryIIIA Meloidogyne spp. B.326 CryIIIB2 Adoxophyes spp. B.327 CryIIIB2 Agrotis spp. B.328 CryIIIB2 Alabama argillaceae B.329 CryIIIB2 Anticarsia gemmatalis B.330 CryIIIB2 Chilo spp. B.331 CryIIIB2 Clysia ambiguella B.332 CryIIIB2 Crocidolomia binotalis B.333 CryIIIB2 Cydia spp. B.334 CryIIIB2 Diparopsis castanea B.335 CryIIIB2 Earias spp. B.336 CryIIIB2 Ephestia spp. B.337 CryIIIB2 Heliothis spp. B.338 CryIIIB2 Hellula undalis B.339 CryIIIB2 Keiferia lycopersicella B.340 CryIIIB2 Leucoptera scitella B.341 CryIIIB2 Lithocollethis spp. B.342 CryIIIB2 Lobesia botrana B.343 CryIIIB2 Ostrinia nubilalis B.344 CryIIIB2 Pandemis spp. B.345 CryIIIB2 Pectinophora gossyp. B.346 CryIIIB2 Phyllocnistis citrella B.347 CryIIIB2 Pieris spp. B.348 CryIIIB2 Plutella xylostella B.349 CryIIIB2 Scirpophaga spp. B.350 CryIIIB2 Sesamia spp. B.351 CryIIIB2 Sparganothis spp. B.352 CryIIIB2 Spodoptera spp. B.353 CryIIIB2 Tortrix spp. B.354 CryIIIB2 Trichoplusia ni B.355 CryIIIB2 Agriotes spp. B.356 CryIIIB2 Anthonomus grandis B.357 CryIIIB2 Curculio spp. B.358 CryIIIB2 Diabrotica balteata B.359 CryIIIB2 Leptinotarsa spp. B.360 CryIIIB2 Lissorhoptrus spp. B.361 CryIIIB2 Otiorhynchus spp. B.362 CryIIIB2 Aleurothrixus spp. B.363 CryIIIB2 Aleyrodes spp. B.364 CryIIIB2 Aonidiella spp. B.365 CryIIIB2 Aphididae spp. B.366 CryIIIB2 Aphis spp. B.367 CryIIIB2 Bemisia tabaci B.368 CryIIIB2 Empoasca spp. B.369 CryIIIB2 Mycus spp. B.370 CryIIIB2 Nephotettix spp. B.371 CryIIIB2 Nilaparvata spp. B.372 CryIIIB2 Pseudococcus spp. B.373 CryIIIB2 Psylla spp. B.374 CryIIIB2 Quadraspidiotus spp. B.375 CryIIIB2 Schizaphis spp. B.376 CryIIIB2 Trialeurodes spp. B.377 CryIIIB2 Lyriomyza spp. B.378 CryIIIB2 Oscinella spp. B.379 CryIIIB2 Phorbia spp. B.380 CryIIIB2 Frankliniella spp. B.381 CryIIIB2 Thrips spp. B.382 CryIIIB2 Scirtothrips aurantii B.383 CryIIIB2 Aceria spp. B.384 CryIIIB2 Aculus spp. B.385 CryIIIB2 Brevipalpus spp. B.386 CryIIIB2 Panonychus spp. B.387 CryIIIB2 Phyllocoptruta spp. B.388 CryIIIB2 Tetranychus spp. B.389 CryIIIB2 Heterodera spp. B.390 CryIIIB2 Meloidogyne spp. B.391 CytA Adoxophyes spp. B.392 CytA Agrotis spp. B.393 CytA Alabama argillaceae B.394 CytA Anticarsia gemmatalis B.395 CytA Chilo spp. B.396 CytA Clysia ambiguella B.397 CytA Crocidolomia binotalis B.398 CytA Cydia spp. B.399 CytA Diparopsis castanea B.400 CytA Earias spp. B.401 CytA Ephestia spp. B.402 CytA Heliothis spp. B.403 CytA Hellula undalis B.404 CytA Keiferia lycopersicella B.405 CytA Leucoptera scitella B.406 CytA Lithocollethis spp. B.407 CytA Lobesia botrana B.408 CytA Ostrinia nubilalis B.409 CytA Pandemis spp. B.410 CytA Pectinophora gossyp. B.411 CytA Phyllocnistis citrella B.412 CytA Pieris spp. B.413 CytA Plutella xylostella B.414 CytA Scirpophaga spp. B.415 CytA Sesamia spp. B.416 CytA Sparganothis spp. B.417 CytA Spodoptera spp. B.418 CytA Tortrix spp. B.419 CytA Trichoplusia ni B.420 CytA Agriotes spp. B.421 CytA Anthonomus grandis B.422 CytA Curculio spp. B.423 CytA Diabrotica balteata B.424 CytA Leptinotarsa spp. B.425 CytA Lissorhoptrus spp. B.426 CytA Otiorhynchus spp. B.427 CytA Aleurothrixus spp. B.428 CytA Aleyrodes spp. B.429 CytA Aonidiella spp. B.430 CytA Aphididae spp. B.431 CytA Aphis spp. B.432 CytA Bemisia tabaci B.433 CytA Empoasca spp. B.434 CytA Mycus spp. B.435 CytA Nephotettix spp. B.436 CytA Nilaparvata spp. B.437 CytA Pseudococcus spp. B.438 CytA Psylla spp. B.439 CytA Quadraspidiotus spp. B.440 CytA Schizaphis spp. B.441 CytA Trialeurodes spp. B.442 CytA Lyriomyza spp. B.443 CytA Oscinella spp. B.444 CytA Phorbia spp. B.445 CytA Frankliniella spp. B.446 CytA Thrips spp. B.447 CytA Scirtothrips aurantii B.448 CytA Aceria spp. B.449 CytA Aculus spp. B.450 CytA Brevipalpus spp. B.451 CytA Panonychus spp. B.452 CytA Phyllocoptruta spp. B.453 CytA Tetranychus spp. B.454 CytA Heterodera spp. B.455 CytA Meloidogyne spp. B.456 VIP3 Adoxophyes spp. B.457 VIP3 Agrotis spp. B.458 VIP3 Alabama argillaceae B.459 VIP3 Anticarsia gemmatalis B.460 VIP3 Chilo spp. B.461 VIP3 Clysia ambiguella B.462 VIP3 Crocidolomia binotalis B.463 VIP3 Cydia spp. B.464 VIP3 Diparopsis castanea B.465 VIP3 Earias spp. B.466 VIP3 Ephestia spp. B.467 VIP3 Heliothis spp. B.468 VIP3 Hellula undalis B.469 VIP3 Keiferia lycopersicella B.470 VIP3 Leucoptera scitella B.471 VIP3 Lithocollethis spp. B.472 VIP3 Lobesia botrana B.473 VIP3 Ostrinia nubilalis B.474 VIP3 Pandemis spp. B.475 VIP3 Pectinophora gossyp. B.476 VIP3 Phyllocnistis citrella B.477 VIP3 Pieris spp. B.478 VIP3 Plutella xylostella B.479 VIP3 Scirpophaga spp. B.480 VIP3 Sesamia spp. B.481 VIP3 Sparganothis spp. B.482 VIP3 Spodoptera spp. B.483 VIP3 Tortrix spp. B.484 VIP3 Trichoplusia ni B.485 VIP3 Agriotes spp. B.486 VIP3 Anthonomus grandis B.487 VIP3 Curculio spp. B.488 VIP3 Diabrotica balteata B.489 VIP3 Leptinotarsa spp. B.490 VIP3 Lissorhoptrus spp. B.491 VIP3 Otiorhynchus spp. B.492 VIP3 Aleurothrixus spp. B.493 VIP3 Aleyrodes spp. B.494 VIP3 Aonidiella spp. B.495 VIP3 Aphididae spp. B.496 VIP3 Aphis spp. B.497 VIP3 Bemisia tabaci B.498 VIP3 Empoasca spp. B.499 VIP3 Mycus spp. B.500 VIP3 Nephotettix spp. B.501 VIP3 Nilaparvata spp. B.502 VIP3 Pseudococcus spp. B.503 VIP3 Psylla spp. B.504 VIP3 Quadraspidiotus spp. B.505 VIP3 Schizaphis spp. B.506 VIP3 Trialeurodes spp. B.507 VIP3 Lyriomyza spp. B.508 VIP3 Oscinella spp. B.509 VIP3 Phorbia spp. B.510 VIP3 Frankliniella spp. B.511 VIP3 Thrips spp. B.512 VIP3 Scirtothrips aurantii B.513 VIP3 Aceria spp. B.514 VIP3 Aculus spp. B.515 VIP3 Brevipalpus spp. B.516 VIP3 Panonychus spp. B.517 VIP3 Phyllocoptruta spp. B.518 VIP3 Tetranychus spp. B.519 VIP3 Heterodera spp. B.520 VIP3 Meloidogyne spp. B.521 GL Adoxophyes spp. B.522 GL Agrotis spp. B.523 GL Alabama argillaceae B.524 GL Anticarsia gemmatalis B.525 GL Chilo spp. B.526 GL Clysia ambiguella B.527 GL Crocidolomia binotalis B.528 GL Cydia spp. B.529 GL Diparopsis castanea B.530 GL Earias spp. B.531 GL Ephestia spp. B.532 GL Heliothis spp. B.533 GL Hellula undalis B.534 GL Keiferia lycopersicella B.535 GL Leucoptera scitella B.536 GL Lithocollethis spp. B.537 GL Lobesia botrana B.538 GL Ostrinia nubilalis B.539 GL Pandemis spp. B.540 GL Pectinophora gossyp. B.541 GL Phyllocnistis citrella B.542 GL Pieris spp. B.543 GL Plutella xylostella B.544 GL Scirpophaga spp. B.545 GL Sesamia spp. B.546 GL Sparganothis spp. B.547 GL Spodoptera spp. B.548 GL Tortrix spp. B.549 GL Trichoplusia ni B.550 GL Agriotes spp. B.551 GL Anthonomus grandis B.552 GL Curculio spp. B.553 GL Diabrotica balteata B.554 GL Leptinotarsa spp. B.555 GL Lissorhoptrus spp. B.556 GL Otiorhynchus spp. B.557 GL Aleurothrixus spp. B.558 GL Aleyrodes spp. B.559 GL Aonidiella spp. B.560 GL Aphididae spp. B.561 GL Aphis spp. B.562 GL Bemisia tabaci B.563 GL Empoasca spp. B.564 GL Mycus spp. B.565 GL Nephotettix spp. B.566 GL Nilaparvata spp. B.567 GL Pseudococcus spp. B.568 GL Psylla spp. B.569 GL Quadraspidiotus spp. B.570 GL Schizaphis spp. B.571 GL Trialeurodes spp. B.572 GL Lyriomyza spp. B.573 GL Oscinella spp. B.574 GL Phorbia spp. B.575 GL Frankliniella spp. B.576 GL Thrips spp. B.577 GL Scirtothrips aurantii B.578 GL Aceria spp. B.579 GL Aculus spp. B.580 GL Brevipalpus spp. B.581 GL Panonychus spp. B.582 GL Phyllocoptruta spp. B.583 GL Tetranychus spp. B.584 GL Heterodera spp. B.585 GL Meloidogyne spp. B.586 PL Adoxophyes spp. B.587 PL Agrotis spp. B.588 PL Alabama argillaceae B.589 PL Anticarsia gemmatalis B.590 PL Chilo spp. B.591 PL Clysia ambiguella B.592 PL Crocidolomia binotalis B.593 PL Cydia spp. B.594 PL Diparopsis castanea B.595 PL Earias spp. B.596 PL Ephestia spp. B.597 PL Heliothis spp. B.598 PL Hellula undalis B.599 PL Keiferia lycopersicella B.600 PL Leucoptera scitella B.601 PL Lithocollethis spp. B.602 PL Lobesia botrana B.603 PL Ostrinia nubilalis B.604 PL Pandemis spp. B.605 PL Pectinophora gossyp. B.606 PL Phyllocnistis citrella B.607 PL Pieris spp. B.608 PL Plutella xylostella B.609 PL Scirpophaga spp. B.610 PL Sesamia spp. B.611 PL Sparganothis spp. B.612 PL Spodoptera spp. B.613 PL Tortrix spp. B.614 PL Trichoplusia ni B.615 PL Agriotes spp. B.616 PL Anthonomus grandis B.617 PL Curculio spp. B.618 PL Diabrotica balteata B.619 PL Leptinotarsa spp. B.620 PL Lissorhoptrus spp. B.621 PL Otiorhynchus spp. B.622 PL Aleurothrixus spp. B.623 PL Aleyrodes spp. B.624 PL Aonidiella spp. B.625 PL Aphididae spp. B.626 PL Aphis spp. B.627 PL Bemisia tabaci B.628 PL Empoasca spp. B.629 PL Mycus spp. B.630 PL Nephotettix spp. B.631 PL Nilaparvata spp. B.632 PL Pseudococcus spp. B.633 PL Psylla spp. B.634 PL Quadraspidiotus spp. B.635 PL Schizaphis spp. B.636 PL Trialeurodes spp. B.637 PL Lyriomyza spp. B.638 PL Oscinella spp. B.639 PL Phorbia spp. B.640 PL Frankliniella spp. B.641 PL Thrips spp. B.642 PL Scirtothrips aurantii B.643 PL Aceria spp. B.644 PL Aculus spp. B.645 PL Brevipalpus spp. B.646 PL Panonychus spp. B.647 PL Phyllocoptruta spp. B.648 PL Tetranychus spp. B.649 PL Heterodera spp. B.650 PL Meloidogyne spp. B.651 XN Adoxophyes spp. B.652 XN Agrotis spp. B.653 XN Alabama argillaceae B.654 XN Anticarsia gemmatalis B.655 XN Chilo spp. B.656 XN Clysia ambiguella B.657 XN Crocidolomia binotalis B.658 XN Cydia spp. B.659 XN Diparopsis castanea B.660 XN Earias spp. B.661 XN Ephestia spp. B.662 XN Heliothis spp. B.663 XN Hellula undalis B.664 XN Keiferia lycopersicella B.665 XN Leucoptera scitella B.666 XN Lithocollethis spp. B.667 XN Lobesia botrana B.668 XN Ostrinia nubilalis B.669 XN Pandemis spp. B.670 XN Pectinophora gossyp. B.671 XN Phyllocnistis citrella B.672 XN Pieris spp. B.673 XN Plutella xylostella B.674 XN Scirpophaga spp. B.675 XN Sesamia spp. B.676 XN Sparganothis spp. B.677 XN Spodoptera spp. B.678 XN Tortrix spp. B.679 XN Trichoplusia ni B.680 XN Agriotes spp. B.681 XN Anthonomus grandis B.682 XN Curculio spp. B.683 XN Diabrotica balteata B.684 XN Leptinotarsa spp. B.685 XN Lissorhoptrus spp. B.686 XN Otiorhynchus spp. B.687 XN Aleurothrixus spp. B.688 XN Aleyrodes spp. B.689 XN Aonidiella spp. B.690 XN Aphididae spp. B.691 XN Aphis spp. B.692 XN Bemisia tabaci B.693 XN Empoasca spp. B.694 XN Mycus spp. B.695 XN Nephotettix spp. B.696 XN Nilaparvata spp. B.697 XN Pseudococcus spp. B.698 XN Psylla spp. B.699 XN Quadraspidiotus spp. B.700 XN Schizaphis spp. B.701 XN Trialeurodes spp. B.702 XN Lyriomyza spp. B.703 XN Oscinella spp. B.704 XN Phorbia spp. B.705 XN Frankliniella spp. B.706 XN Thrips spp. B.707 XN Scirtothrips aurantii B.708 XN Aceria spp. B.709 XN Aculus spp. B.710 XN Brevipalpus spp. B.711 XN Panonychus spp. B.712 XN Phyllocoptruta spp. B.713 XN Tetranychus spp. B.714 XN Heterodera spp. B.715 XN Meloidogyne spp. B.716 PInh. Adoxophyes spp. B.717 PInh. Agrotis spp. B.718 PInh. Alabama argillaceae B.719 PInh. Anticarsia gemmatalis B.720 PInh. Chilo spp. B.721 PInh. Clysia ambiguella B.722 PInh. Crocidolomia binotalis B.723 PInh. Cydia spp. B.724 PInh. Diparopsis castanea B.725 PInh. Earias spp. B.726 PInh. Ephestia spp. B.727 PInh. Heliothis spp. B.728 PInh. Hellula undalis B.729 PInh. Keiferia lycopersicella B.730 PInh. Leucoptera scitella B.731 PInh. Lithocollethis spp. B.732 PInh. Lobesia botrana B.733 PInh. Ostrinia nubilalis B.734 PInh. Pandemis spp. B.735 PInh. Pectinophora gossyp. B.736 PInh. Phyllocnistis citrella B.737 PInh. Pieris spp. B.738 PInh. Plutella xylostella B.739 PInh. Scirpophaga spp. B.740 PInh. Sesamia spp. B.741 PInh. Sparganothis spp. B.742 PInh. Spodoptera spp. B.743 PInh. Tortrix spp. B.744 PInh. Trichoplusia ni B.745 PInh. Agriotes spp. B.746 PInh. Anthonomus grandis B.747 PInh. Curculio spp. B.748 PInh. Diabrotica balteata B.749 PInh. Leptinotarsa spp. B.750 PInh. Lissorhoptrus spp. B.751 PInh. Otiorhynchus spp. B.752 PInh. Aleurothrixus spp. B.753 PInh. Aleyrodes spp. B.754 PInh. Aonidiella spp. B.755 PInh. Aphididae spp. B.756 PInh. Aphis spp. B.757 PInh. Bemisia tabaci B.758 PInh. Empoasca spp. B.759 PInh. Mycus spp. B.760 PInh. Nephotettix spp. B.761 PInh. Nilaparvata spp. B.762 PInh. Pseudococcus spp. B.763 PInh. Psylla spp. B.764 PInh. Quadraspidiotus spp. B.765 PInh. Schizaphis spp. B.766 PInh. Trialeurodes spp. B.767 PInh. Lyriomyza spp. B.768 PInh. Oscinella spp. B.769 PInh. Phorbia spp. B.770 PInh. Frankliniella spp. B.771 PInh. Thrips spp. B.772 PInh. Scirtothrips aurantii B.773 PInh. Aceria spp. B.774 PInh. Aculus spp. B.775 PInh. Brevipalpus spp. B.776 PInh. Panonychus spp. B.777 PInh. Phyllocoptruta spp. B.778 PInh. Tetranychus spp. B.779 PInh. Heterodera spp. B.780 PInh. Meloidogyne spp. B.781 Plec Adoxophyes spp. B.782 Plec Agrotis spp. B.783 Plec Alabama argillaceae B.784 Plec Anticarsia gemmatalis B.785 Plec Chilo spp. B.786 Plec Clysia ambiguella B.787 Plec Crocidolomia binotalis B.788 Plec Cydia spp. B.789 Plec Diparopsis castanea B.790 Plec Earias spp. B.791 Plec Ephestia spp. B.792 Plec Heliothis spp. B.793 Plec Hellula undalis B.794 Plec Keiferia lycopersicella B.795 Plec Leucoptera scitella B.796 Plec Lithocollethis spp. B.797 Plec Lobesia botrana B.798 Plec Ostrinia nubilalis B.799 Plec Pandemis spp. B.800 Plec Pectinophora gossyp. B.801 Plec Phyllocnistis citrella B.802 Plec Pieris spp. B.803 Plec Plutella xylostella B.804 Plec Scirpophaga spp. B.805 Plec Sesamia spp. B.806 Plec Sparganothis spp. B.807 Plec Spodoptera spp. B.808 Plec Tortrix spp. B.809 Plec Trichoplusia ni B.810 Plec Agriotes spp. B.811 Plec Anthonomus grandis B.812 Plec Curculio spp. B.813 Plec Diabrotica balteata B.814 Plec Leptinotarsa spp. B.815 Plec Lissorhoptrus spp. B.816 Plec Otiorhynchus spp. B.817 Plec Aleurothrixus spp. B.818 Plec Aleyrodes spp. B.819 Plec Aonidiella spp. B.820 Plec Aphididae spp. B.821 Plec Aphis spp. B.822 Plec Bemisia tabaci B.823 Plec Empoasca spp. B.824 Plec Mycus spp. B.825 Plec Nephotettix spp. B.826 Plec Nilaparvata spp. B.827 Plec Pseudococcus spp. B.828 Plec Psylla spp. B.829 Plec Quadraspidiotus spp. B.830 Plec Schizaphis spp. B.831 Plec Trialeurodes spp. B.832 Plec Lyriomyza spp. B.833 Plec Oscinella spp. B.834 Plec Phorbia spp. B.835 Plec Frankliniella spp. B.836 Plec Thrips spp. B.837 Plec Scirtothrips aurantii B.838 Plec Aceria spp. B.839 Plec Aculus spp. B.840 Plec Brevipalpus spp. B.841 Plec Panonychus spp. B.842 Plec Phyllocoptruta spp. B.843 Plec Tetranychus spp. B.844 Plec Heterodera spp. B.845 Plec Meloidogyne spp. B.846 AggI. Adoxophyes spp. B.847 AggI. Agrotis spp. B.848 AggI. Alabama argillaceae B.849 AggI. Anticarsia gemmatalis B.850 AggI. Chilo spp. B.851 AggI. Clysia ambiguella B.852 AggI. Crocidolomia binotalis B.853 AggI. Cydia spp. B.854 AggI. Diparopsis castanea B.855 AggI. Earias spp. B.856 AggI. Ephestia spp. B.857 AggI. Heliothis spp. B.858 AggI. Hellula undalis B.859 AggI. Keiferia lycopersicella B.860 AggI. Leucoptera scitella B.861 AggI. Lithocollethis spp. B.862 AggI. Lobesia botrana B.863 AggI. Ostrinia nubilalis B.864 AggI. Pandemis spp. B.865 AggI. Pectinophora gossyp. B.866 AggI. Phyllocnistis citrella B.867 AggI. Pieris spp. B.868 AggI. Plutella xylostella B.869 AggI. Scirpophaga spp. B.870 AggI. Sesamia spp. B.871 AggI. Sparganothis spp. B.872 AggI. Spodoptera spp. B.873 AggI. Tortrix spp. B.874 AggI. Trichoplusia ni B.875 AggI. Agriotes spp. B.876 AggI. Anthonomus grandis B.877 AggI. Curculio spp. B.878 AggI. Diabrotica balteata B.879 AggI. Leptinotarsa spp. B.880 AggI. Lissorhoptrus spp. B.881 AggI. Otiorhynchus spp. B.882 AggI. Aleurothrixus spp. B.883 AggI. Aleyrodes spp. B.884 AggI. Aonidiella spp. B.885 AggI. Aphididae spp. B.886 AggI. Aphis spp. B.887 AggI. Bemisia tabaci B.888 AggI. Empoasca spp. B.889 AggI. Mycus spp. B.890 AggI. Nephotettix spp. B.891 AggI. Nilaparvata spp. B.892 AggI. Pseudococcus spp. B.893 AggI. Psylla spp. B.894 AggI. Quadraspidiotus spp. B.895 AggI. Schizaphis spp. B.896 AggI. Trialeurodes spp. B.897 AggI. Lyriomyza spp. B.898 AggI. Oscinella spp. B.899 AggI. Phorbia spp. B.900 AggI. Frankliniella spp. B.901 AggI. Thrips spp. B.902 AggI. Scirtothrips aurantii B.903 AggI. Aceria spp. B.904 AggI. Aculus spp. B.905 AggI. Brevipalpus spp. B.906 AggI. Panonychus spp. B.907 AggI. Phyllocoptruta spp. B.908 AggI. Tetranychus spp. B.909 AggI. Heterodera spp. B.910 AggI. Meloidogyne spp. B.911 CO Adoxophyes spp. B.912 CO Agrotis spp. B.913 CO Alabama argillaceae B.914 CO Anticarsia gemmatalis B.915 CO Chilo spp. B.916 CO Clysia ambiguella B.917 CO Crocidolomia binotalis B.918 CO Cydia spp. B.919 CO Diparopsis castanea B.920 CO Earias spp. B.921 CO Ephestia spp. B.922 CO Heliothis spp. B.923 CO Hellula undalis B.924 CO Keiferia lycopersicella B.925 CO Leucoptera scitella B.926 CO Lithocollethis spp. B.927 CO Lobesia botrana B.928 CO Ostrinia nubilalis B.929 CO Pandemis spp. B.930 CO Pectinophora gossyp. B.931 CO Phyllocnistis citrella B.932 CO Pieris spp. B.933 CO Plutella xylostella B.934 CO Scirpophaga spp. B.935 CO Sesamia spp. B.936 CO Sparganothis spp. B.937 CO Spodoptera spp. B.938 CO Tortrix spp. B.939 CO Trichoplusia ni B.940 CO Agriotes spp. B.941 CO Anthonomus grandis B.942 CO Curculio spp. B.943 CO Diabrotica balteata B.944 CO Leptinotarsa spp. B.945 CO Lissorhoptrus spp. B.946 CO Otiorhynchus spp. B.947 CO Aleurothrixus spp. B.948 CO Aleyrodes spp. B.949 CO Aonidiella spp. B.950 CO Aphididae spp. B.951 CO Aphis spp. B.952 CO Bemisia tabaci B.953 CO Empoasca spp. B.954 CO Mycus spp. B.955 CO Nephotettix spp. B.956 CO Nilaparvata spp. B.957 CO Pseudococcus spp. B.958 CO Psylla spp. B.959 CO Quadraspidiotus spp. B.960 CO Schizaphis spp. B.961 CO Trialeurodes spp. B.962 CO Lyriomyza spp. B.963 CO Oscinella spp. B.964 CO Phorbia spp. B.965 CO Frankliniella spp. B.966 CO Thrips spp. B.967 CO Scirtothrips aurantii B.968 CO Aceria spp. B.969 CO Aculus spp. B.970 CO Brevipalpus spp. B.971 CO Panonychus spp. B.972 CO Phyllocoptruta spp. B.973 CO Tetranychus spp. B.974 CO Heterodera spp. B.975 CO Meloidogyne spp. B.976 CH Adoxophyes spp. B.977 CH Agrotis spp. B.978 CH Alabama argillaceae B.979 CH Anticarsia gemmatalis B.980 CH Chilo spp. B.981 CH Clysia ambiguella B.982 CH Crocidolomia binotalis B.983 CH Cydia spp. B.984 CH Diparopsis castanea B.985 CH Earias spp. B.986 CH Ephestia spp. B.987 CH Heliothis spp. B.988 CH Hellula undalis B.989 CH Keiferia lycopersicella B.990 CH Leucoptera scitella B.991 CH Lithocollethis spp. B.992 CH Lobesia botrana B.993 CH Ostrinia nubilalis B.994 CH Pandemis spp. B.995 CH Pectinophora gossyp. B.996 CH Phyllocnistis citrella B.997 CH Pieris spp. B.998 CH Plutella xylostella B.999 CH Scirpophaga spp. B.1000 CH Sesamia spp. B.1001 CH Sparganothis spp. B.1002 CH Spodoptera spp. B.1003 CH Tortrix spp. B.1004 CH Trichoplusia ni B.1005 CH Agriotes spp. B.1006 CH Anthonomus grandis B.1007 CH Curculio spp. B.1008 CH Diabrotica balteata B.1009 CH Leptinotarsa spp. B.1010 CH Lissorhoptrus spp. B.1011 CH Otiorhynchus spp. B.1012 CH Aleurothrixus spp. B.1013 CH Aleyrodes spp. B.1014 CH Aonidiella spp. B.1015 CH Aphididae spp. B.1016 CH Aphis spp. B.1017 CH Bemisia tabaci B.1018 CH Empoasca spp. B.1019 CH Mycus spp. B.1020 CH Nephotettix spp. B.1021 CH Nilaparvata spp. B.1022 CH Pseudococcus spp. B.1023 CH Psylla spp. B.1024 CH Quadraspidiotus spp. B.1025 CH Schizaphis spp. B.1026 CH Trialeurodes spp. B.1027 CH Lyriomyza spp. B.1028 CH Oscinella spp. B.1029 CH Phorbia spp. B.1030 CH Frankliniella spp. B.1031 CH Thrips spp. B.1032 CH Scirtothrips aurantii B.1033 CH Aceria spp. B.1034 CH Aculus spp. B.1035 CH Brevipalpus spp. B.1036 CH Panonychus spp. B.1037 CH Phyllocoptruta spp. B.1038 CH Tetranychus spp. B.1039 CH Heterodera spp. B.1040 CH Meloidogyne spp. B.1041 SS Adoxophyes spp. B.1042 SS Agrotis spp. B.1043 SS Alabama argillaceae B.1044 SS Anticarsia gemmatalis B.1045 SS Chilo spp. B.1046 SS Clysia ambiguella B.1047 SS Crocidolomia binotalis B.1048 SS Cydia spp. B.1049 SS Diparopsis castanea B.1050 SS Earias spp. B.1051 SS Ephestia spp. B.1052 SS Heliothis spp. B.1053 SS Hellula undalis B.1054 SS Keiferia lycopersicella B.1055 SS Leucoptera scitella B.1056 SS Lithocollethis spp. B.1057 SS Lobesia botrana B.1058 SS Ostrinia nubilalis B.1059 SS Pandemis spp. B.1060 SS Pectinophora gossyp. B.1061 SS Phyllocnistis citrella B.1062 SS Pieris spp. B.1063 SS Plutella xylostella B.1064 SS Scirpophaga spp. B.1065 SS Sesamia spp. B.1066 SS Sparganothis spp. B.1067 SS Spodoptera spp. B.1068 SS Tortrix spp. B.1069 SS Trichoplusia ni B.1070 SS Agriotes spp. B.1071 SS Anthonomus grandis B.1072 SS Curculio spp. B.1073 SS Diabrotica balteata B.1074 SS Leptinotarsa spp. B.1075 SS Lissorhoptrus spp. B.1076 SS Otiorhynchus spp. B.1077 SS Aleurothrixus spp. B.1078 SS Aleyrodes spp. B.1079 SS Aonidiella spp. B.1080 SS Aphididae spp. B.1081 SS Aphis spp. B.1082 SS Bemisia tabaci B.1083 SS Empoasca spp. B.1084 SS Mycus spp. B.1085 SS Nephotettix spp. B.1086 SS Nilaparvata spp. B.1087 SS Pseudococcus spp. B.1088 SS Psylla spp. B.1089 SS Quadraspidiotus spp. B.1090 SS Schizaphis spp. B.1091 SS Trialeurodes spp. B.1092 SS Lyriomyza spp. B.1093 SS Oscinella spp. B.1094 SS Phorbia spp. B.1095 SS Frankliniella spp. B.1096 SS Thrips spp. B.1097 SS Scirtothrips aurantii B.1098 SS Aceria spp. B.1099 SS Aculus spp. B.1100 SS Brevipalpus spp. B.1101 SS Panonychus spp. B.1102 SS Phyllocoptruta spp. B.1103 SS Tetranychus spp. B.1104 SS Heterodera spp. B.1105 SS Meloidogyne spp. B.1106 HO Adoxophyes spp. B.1107 HO Agrotis spp. B.1108 HO Alabama argillaceae B.1109 HO Anticarsia gemmatalis B.1110 HO Chilo spp. B.1111 HO Clysia ambiguella B.1112 HO Crocidolomia binotalis B.1113 HO Cydia spp. B.1114 HO Diparopsis castanea B.1115 HO Earias spp. B.1116 HO Ephestia spp. B.1117 HO Heliothis spp. B.1118 HO Hellula undalis B.1119 HO Keiferia lycopersicella B.1120 HO Leucoptera scitella B.1121 HO Lithocollethis spp. B.1122 HO Lobesia botrana B.1123 HO Ostrinia nubilalis B.1124 HO Pandemis spp. B.1125 HO Pectinophora gossypiella B.1126 HO Phyllocnistis citrella B.1127 HO Pieris spp. B.1128 HO Plutella xylostella B.1129 HO Scirpophaga spp. B.1130 HO Sesamia spp. B.1131 HO Sparganothis spp. B.1132 HO Spodoptera spp. B.1133 HO Tortrix spp. B.1134 HO Trichoplusia ni B.1135 HO Agriotes spp. B.1136 HO Anthonomus grandis B.1137 HO Curculio spp. B.1138 HO Diabrotica balteata B.1139 HO Leptinotarsa spp. B.1140 HO Lissorhoptrus spp. B.1141 HO Otiorhynchus spp. B.1142 HO Aleurothrixus spp. B.1143 HO Aleyrodes spp. B.1144 HO Aonidiella spp. B.1145 HO Aphididae spp. B.1146 HO Aphis spp. B.1147 HO Bemisia tabaci B.1148 HO Empoasca spp. B.1149 HO Mycus spp. B.1150 HO Nephotettix spp. B.1151 HO Nilaparvata spp. B.1152 HO Pseudococcus spp. B.1153 HO Psylla spp. B.1154 HO Quadraspidiotus spp. B.1155 HO Schizaphis spp. B.1156 HO Trialeurodes spp. B.1157 HO Lyriomyza spp. B.1158 HO Oscinella spp. B.1159 HO Phorbia spp. B.1160 HO Frankliniella spp. B.1161 HO Thrips spp. B.1162 HO Scirtothrips aurantii B.1163 HO Aceria spp. B.1164 HO Aculus spp. B.1165 HO Brevipalpus spp. B.1166 HO Panonychus spp. B.1167 HO Phyllocoptruta spp. B.1168 HO Tetranychus spp. B.1169 HO Heterodera spp. B.1170 HO Meloidogyne spp. The following abreviations are used in the table: Active Principle of transgenic plant: AP Photorhabdus luminescens: PL Xenorhabdus nematophilus: XN Proteinase Inhibitors: PInh. Plant lectins Plec Agglutinins: Aggl. 3-Hydroxysteroid oxidase: HO Cholesteroloxidase: CO Chitinase: CH Glucanase: GL Stilbensynthase SS

BIOLOGICAL EXAMPLES

Table 1: A method of controlling pests comprising the application of Abamectin to transgenic cotton, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 2: A method of controlling pests comprising the application of Abamectin to transgenic rice, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 3: A method of controlling pests comprising the application of Abamectin to transgenic potatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 4: A method of controlling pests comprising the application of Abamectin to transgenic brassica, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 5: A method of controlling pests comprising the application of Abamectin to transgenic tomatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 6: A method of controlling pests comprising the application of Abamectin to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 7: A method of controlling pests comprising the application of Abamectin to transgenic soybeans, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 8: A method of controlling pests comprising the application of Abamectin to transgenic maize, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 9: A method of controlling pests comprising the application of Abamectin to transgenic wheat, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 10: A method of controlling pests comprising the application of Abamectin to transgenic bananas, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 11: A method of controlling pests comprising the application of Abamectin to transgenic citrus trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 12: A method of controlling pests comprising the application of Abamectin to transgenic pome fruit trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 13: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic cotton, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 14: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic rice, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 15: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic potatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 16: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic tomatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 17: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 18: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic soybeans, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 19: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic maize, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 20: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic wheat, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 21: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic bananas, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 22: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic orange trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 23: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic pome fruit, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 24: A method of controlling pests comprising the application of Emamectin-Benzoate to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 25: A method of controlling pests comprising the application of Spinosad to transgenic cotton, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 26: A method of controlling pests comprising the application of Spinosad to transgenic rice, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 27: A method of controlling pests comprising the application of Spinosad to transgenic potatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 28: A method of controlling pests comprising the application of Spinosad to transgenic brassica, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 29: A method of controlling pests comprising the application of Spinosad to transgenic tomatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 30: A method of controlling pests comprising the application of Spinosad to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 31: A method of controlling pests comprising the application of Spinosad to transgenic soybeans, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 32: A method of controlling pests comprising the application of Spinosad to transgenic maize, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 33: A method of controlling pests comprising the application of Spinosad to transgenic wheat, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 34: A method of controlling pests comprising the application of Spinosad to transgenic bananas, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 35: A method of controlling pests comprising the application of Spinosad to transgenic citrus trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

Table 36: A method of controlling pests comprising the application of Spinosad to transgenic pome fruit trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to a line of the table B.

TABLE C Principle Tolerant to Crop C.1 ALS Sulfonylureas etc. *** Cotton C.2 ALS Sulfonylureas etc. *** Rice C.3 ALS Sulfonylureas etc. *** Brassica C.4 ALS Sulfonylureas etc. *** Potatoes C.5 ALS Sulfonylureas etc. *** Tomatoes C.6 ALS Sulfonylureas etc. *** Cucurbits C.7 ALS Sulfonylureas etc. *** Soybeans C.8 ALS Sulfonylureas etc. *** Maize C.9 ALS Sulfonylureas etc. *** Wheat C.10 ALS Sulfonylureas etc. *** pome fruit C.11 ALS Sulfonylureas etc. *** stone fruit C.12 ALS Sulfonylureas etc. *** citrus C.13 ACCase +++ Cotton C.14 ACCase +++ Rice C.15 ACCase +++ Brassica C.16 ACCase +++ Potatoes C.17 ACCase +++ Tomatoes C.18 ACCase +++ Cucurbits C.19 ACCase +++ Soybeans C.20 ACCase +++ Maize C.21 ACCase +++ Wheat C.22 ACCase +++ pome fruit C.23 ACCase +++ stone fruit C.24 ACCase +++ citrus C.25 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Cotton Mesotrion C.26 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Rice Mesotrion C.27 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Brassica Mesotrion C.28 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Potatoes Mesotrion C.29 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Tomatoes Mesotrion C.30 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Cucurbits Mesotrion C.31 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Soybeans Mesotrion C.32 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Maize Mesotrion C.33 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Wheat Mesotrion C.34 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, pome fruit Mesotrion C.35 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, stone fruit Mesotrion C.36 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, citrus Mesotrion C.37 Nitrilase Bromoxynil, Ioxynil Cotton C.38 Nitrilase Bromoxynil, Ioxynil Rice C.39 Nitrilase Bromoxynil, Ioxynil Brassica C.40 Nitrilase Bromoxynil, Ioxynil Potatoes C.41 Nitrilase Bromoxynil, Ioxynil Tomatoes C.42 Nitrilase Bromoxynil, Ioxynil Cucurbits C.43 Nitrilase Bromoxynil, Ioxynil Soybeans C.44 Nitrilase Bromoxynil, Ioxynil Maize C.45 Nitrilase Bromoxynil, Ioxynil Wheat C.46 Nitrilase Bromoxynil, Ioxynil pome fruit C.47 Nitrilase Bromoxynil, Ioxynil stone fruit C.48 Nitrilase Bromoxynil, Ioxynil citrus C.49 IPS Chloroactanilides &&& Cotton C.50 IPS Chloroactanilides &&& Rice C.51 IPS Chloroactanilide &&&s Brassica C.52 IPS Chloroactanilides &&& Potatoes C.53 IPS Chloroactanilides &&& Tomatoes C.54 IPS Chloroactanilides &&& Cucurbits C.55 IPS Chloroactanilides &&& Soybeans C.56 IPS Chloroactanilides &&& Maize C.57 IPS Chloroactanilides &&& Wheat C.58 IPS Chloroactanilides &&& pome fruit C.59 IPS Chloroactanilides &&& stone fruit C.60 IPS Chloroactanilides &&& citrus C.61 HOM 2,4-D, Mecoprop-P Cotton C.62 HOM 2,4-D, Mecoprop-P Rice C.63 HOM 2,4-D, Mecoprop-P Brassica C.64 HOM 2,4-D, Mecoprop-P Potatoes C.65 HOM 2,4-D, Mecoprop-P Tomatoes C.66 HOM 2,4-D, Mecoprop-P Cucurbits C.67 HOM 2,4-D, Mecoprop-P Soybeans C.68 HOM 2,4-D, Mecoprop-P Maize C.69 HOM 2,4-D, Mecoprop-P Wheat C.70 HOM 2,4-D, Mecoprop-P pome fruit C.71 HOM 2,4-D, Mecoprop-P stone fruit C.72 HOM 2,4-D, Mecoprop-P citrus C.73 PROTOX Protox inhibitors /// Cotton C.74 PROTOX Protox inhibitors /// Rice C.75 PROTOX Protox inhibitors /// Brassica C.76 PROTOX Protox inhibitors /// Potatoes C.77 PROTOX Protox inhibitors /// Tomatoes C.78 PROTOX Protox inhibitors /// Cucurbits C.79 PROTOX Protox inhibitors /// Soybeans C.80 PROTOX Protox inhibitors /// Maize C.81 PROTOX Protox inhibitors /// Wheat C.82 PROTOX Protox inhibitors /// pome fruit C.83 PROTOX Protox inhibitors /// stone fruit C.84 PROTOX Protox inhibitors /// citrus C.85 EPSPS Glyphosate and/or Sulphosate Cotton C.86 EPSPS Glyphosate and/or Sulphosate Rice C.87 EPSPS Glyphosate and/or Sulphosate Brassica C.88 EPSPS Glyphosate and/or Sulphosate Potatoes C.89 EPSPS Glyphosate and/or Sulphosate Tomatoes C.90 EPSPS Glyphosate and/or Sulphosate Cucurbits C.91 EPSPS Glyphosate and/or Sulphosate Soybeans C.92 EPSPS Glyphosate and/or Sulphosate Maize C.93 EPSPS Glyphosate and/or Sulphosate Wheat C.94 EPSPS Glyphosate and/or Sulphosate pome fruit C.95 EPSPS Glyphosate and/or Sulphosate stone fruit C.96 EPSPS Glyphosate and/or Sulphosate citrus C.97 GS Gluphosinate and/or Bialaphos Cotton C.98 GS Gluphosinate and/or Bialaphos Rice C.99 GS Gluphosinate and/or Bialaphos Brassica C.100 GS Gluphosinate and/or Bialaphos Potatoes C.101 GS Gluphosinate and/or Bialaphos Tomatoes C.102 GS Gluphosinate and/or Bialaphos Cucurbits C.103 GS Gluphosinate and/or Bialaphos Soybeans C.104 GS Gluphosinate and/or Bialaphos Maize C.105 GS Gluphosinate and/or Bialaphos Wheat C.106 GS Gluphosinate and/or Bialaphos pome fruit C.107 GS Gluphosinate and/or Bialaphos stone fruit C.108 GS Gluphosinate and/or Bialaphos citrus Abbreviations: Acetyl-COA Carboxylase: ACCase Acetolactate Synthase: ALS Hydroxyphenylpyruvat dioxygenase: HPPD Inhibition of protein synthesis: IPS Hormone mimic: HO Glutamine Synthetase: GS Protoporphyrinogen oxidase: PROTOX 5-Enolpyruvyl-3-Phosphoshikimate Synthase: EPSPS ***Included are Sulfonylureas, Imidazolinones, Triazolopyrimidines, Dimethoxypyrimidines and N-Acylsulfonamides: Sulfonylureas such as Chlorsulfuron, Chlorimuron, Ethamethsulfuron, Metsulfuron, Primisulfuron, Prosulfuron, Triasulfuron, Cinosulfuron, Trifusulfuron, Oxasulfuron, Bensulfuron, Tribenuron, ACC 322140, Fluzasulfuron, Ethoxysulfuron, Fluzasdulfuron, Nicosulfuron, Rimsulfuron, Thifensulfuron, Pyrazosulfuron, Clopyrasulfuron, NC 330, Azimsulfuron, Imazosulfuron, Sulfosulfuron, Amidosulfuron, Flupyrsulfuron, CGA 362622 Imidazolinones such as Imazamethabenz, Imazaquin, Imazamethypyr, Imazethapyr, Imazapyr and Imazamox; Triazolopyrimidines such as DE 511, Flumetsulam and Chloransulam; Dimethoxypyrimidines such as Pyrithiobac, Pyriminobac, Bispyribac and Pyribenzoxim. +++ Tolerant to Diclofop-methyl, Fluazifop-P-butyl, Haloxyfop-P-methyl, Haloxyfop-P-ethyl, Quizalafop-P-ethyl, clodinafop propargyl, fenoxaprop--ethyl, -Tepraloxydim, Alloxydim, Sethoxydim, Cycloxydim, Cloproxydim, Tralkoxydim, Butoxydim, Caloxydim, Clefoxydim, Clethodim. &&& Chloroacetanilides such as Alachlor Acetochlor, Dimethenamid /// Protox inhibitors: For instance diphenyethers such as Acifluorfen, Aclonifen, Bifenox, Chlornitrofen, Ethoxyfen, Fluoroglycofen, Fomesafen, Lactofen, Oxyfluorfen; Imides such as Azafenidin, Carfentrazone-ethyl, Cinidon-ethyl, Flumiclorac-pentyl, Flumioxazin, Fluthiacet-methyl, Oxadiargyl, Oxadiazon, Pentoxazone, Sulfentrazone, Imides and others, such as Flumipropyn, Flupropacil, Nipyraclofen and Thidiazimin; and further Fluazolate and Pyraflufen-ethyl

BIOLOGICAL EXAMPLES

Table 39: A method of controlling representatives of the genus Adoxophyes comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 40: A method of controlling representatives of the genus Agrotis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 41: A method of controlling Alabama argillaceae comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 42: A method of controlling Anticarsia gemmatalis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 43: A method of controlling representatives of the genus Chilo comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 44: A method of controlling Clysia ambiguella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 45: A method of controlling representatives of the genus Cnephalocrocis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 46: A method of controlling Crocidolomia binotalis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 47: A method of controlling representatives of the genus Cydia comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 48: A method of controlling Diparopsis castanea comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 49: A method of controlling representatives of the genus Earias comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 50: A method of controlling representatives of the genus Ephestia comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 51: A method of controlling representatives of the genus Heliothis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 52: A method of controlling Hellula undalis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 53: A method of controlling Keiferia lycopersicella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 54: A method of controlling Leucoptera scitella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 55: A method of controlling representatives of the genus Lithocollethis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 56: A method of controlling Lobesia botrana comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 57: A method of controlling Ostrinia nubilalis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 58: A method of controlling representatives of the genus Pandemis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 59: A method of controlling Pectinophora gossypiella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 60: A method of controlling Phyllocnistis citrella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 61: A method of controlling representatives of the genus Pieris comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 62: A method of controlling Plutella xylostella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 63: A method of controlling representatives of the genus Scirpophaga comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 64: A method of controlling representatives of the genus Sesamia comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 65: A method of controlling representatives of the genus Sparganothis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 66: A method of controlling representatives of the genus Spodoptera comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 67: A method of controlling representatives of the genus Tortrix comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 68: A method of controlling Trichoplusia ni comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 69: A method of controlling representatives of the genus Agriotes comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 70: A method of controlling Anthonomus grandis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 71: A method of controlling representatives of the genus Curculio comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 72: A method of controlling Diabrotica balteata comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 73: A method of controlling representatives of the genus Leptinotarsa comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 74: A method of controlling representatives of the genus Lissorhoptrus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 75: A method of controlling representatives of the genus Otiorhynchus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 76: A method of controlling representatives of the genus Aleurothrixus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 77: A method of controlling representatives of the genus Aleyrodes comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 78: A method of controlling representatives of the genus Aonidiella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 79: A method of controlling representatives of the family Aphididae comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 80: A method of controlling representatives of the genus Aphis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 81: A method of controlling Bemisia tabaci comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 82: A method of controlling representatives of the genus Empoasca comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 83: A method of controlling representatives of the genus Mycus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 84: A method of controlling representatives of the genus Nephotettix comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 85: A method of controlling representatives of the genus Nilaparvata comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 86: A method of controlling representatives of the genus Pseudococcus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 87: A method of controlling representatives of the genus Psylla comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 88: A method of controlling representatives of the genus Quadraspidiotus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 89: A method of controlling representatives of the genus Schizaphis comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 90: A method of controlling representatives of the genus Trialeurodes comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 91: A method of controlling representatives of the genus Lyriomyza comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 92: A method of controlling representatives of the genus Oscinella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 93: A method of controlling representatives of the genus Phorbia comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 94: A method of controlling representatives of the genus Frankliniella comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 95: A method of controlling representatives of the genus Thrips comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 96: A method of controlling Scirtothrips aurantii comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 97: A method of controlling representatives of the genus Aceria comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 98: A method of controlling representatives of the genus Aculus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 99: A method of controlling representatives of the genus Brevipalpus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 100: A method of controlling representatives of the genus Panonychus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 101: A method of controlling representatives of the genus Phyllocoptruta comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 102: A method of controlling representatives of the genus Tetranychus comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 103: A method of controlling representatives of the genus Heterodera comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 104: A method of controlling representatives of the genus Meloidogyne comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 105: A method of controlling Mamestra brassica comprising the application of Abamectin to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 106: A method of controlling representatives of the genus Adoxophyes comprising the application of Emamectin-Benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 107: A method of controlling representatives of the genus Agrotis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 108: A method of controlling Alabama argillaceae comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 109: A method of controlling Anticarsia gemmatalis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 110: A method of controlling representatives of the genus Chilo comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 111: A method of controlling Clysia ambiguella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 112: A method of controlling representatives of the genus Cnephalocrocis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 113: A method of controlling Crocidolomia binotalis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 114: A method of controlling representatives of the genus Cydia comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 115: A method of controlling Diparopsis castanea comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 116: A method of controlling representatives of the genus Earias comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 117: A method of controlling representatives of the genus Ephestia comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 118: A method of controlling representatives of the genus Heliothis of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 119: A method of controlling Hellula undalis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 120: A method of controlling Keiferia lycopersicella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 121: A method of controlling Leucoptera scitella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 122: A method of controlling representatives of the genus Lithocollethis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 123: A method of controlling Lobesia botrana comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 124: A method of controlling Ostrinia nubilalis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 125: A method of controlling representatives of the genus Pandemis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 126: A method of controlling Pectinophora gossypiella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 127: A method of controlling Phyllocnistis citrella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 128: A method of controlling representatives of the genus Pieris comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 129: A method of controlling Plutella xylostella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 130: A method of controlling representatives of the genus Scirpophaga comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 131: A method of controlling representatives of the genus Sesamia comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 132: A method of controlling representatives of the genus Sparganothis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 133: A method of controlling representatives of the genus Spodoptera comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 134: A method of controlling representatives of the genus Tortrix comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 135: A method of controlling Trichoplusia ni comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 136: A method of controlling representatives of the genus Agriotes comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 137: A method of controlling Anthonomus grandis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 138: A method of controlling representatives of the genus Curculio comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 139: A method of controlling Diabrotica balteata comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 140: A method of controlling representatives of the genus Leptinotarsa comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 141: A method of controlling representatives of the genus Lissorhoptrus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 142: A method of controlling representatives of the genus Otiorhynchus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 143: A method of controlling representatives of the genus Aleurothrixus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 144: A method of controlling representatives of the genus Aleyrodes comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 145: A method of controlling representatives of the genus Aonidiella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 146: A method of controlling representatives of the family Aphididae comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 147: A method of controlling representatives of the genus Aphis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 148: A method of controlling Bemisia tabaci comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 149: A method of controlling representatives of the genus Empoasca comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 150: A method of controlling representatives of the genus Mycus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 151: A method of controlling representatives of the genus Nephotettix comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 152: A method of controlling representatives of the genus Nilaparvata comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 153: A method of controlling representatives of the genus Pseudococcus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 154: A method of controlling representatives of the genus Psylla comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 155: A method of controlling representatives of the genus Quadraspidiotus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 156: A method of controlling representatives of the genus Schizaphis comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 157: A method of controlling representatives of the genus Trialeurodes comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 158: A method of controlling representatives of the genus Lyriomyza comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 159: A method of controlling representatives of the genus Oscinella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 160: A method of controlling representatives of the genus Phorbia comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 161: A method of controlling representatives of the genus Frankliniella comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 162: A method of controlling representatives of the genus Thrips comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 163: A method of controlling Scirtothrips aurantii comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 164: A method of controlling representatives of the genus Aceria comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 165: A method of controlling representatives of the genus Aculus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 166: A method of controlling representatives of the genus Brevipalpus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 167: A method of controlling representatives of the genus Panonychus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 168: A method of controlling representatives of the genus Phyllocoptruta comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 169: A method of controlling representatives of the genus Tetranychus comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 170: A method of controlling representatives of the genus Heterodera comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 171: A method of controlling representatives of the genus Meloidogyne comprising the application of Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 172: A method of controlling representatives of the genus Adoxophyes comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 173: A method of controlling representatives of the genus Agrotis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 174: A method of controlling Alabama argillaceae comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 175: A method of controlling Anticarsia gemmatalis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 176: A method of controlling representatives of the genus Chilo comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 177: A method of controlling Clysia ambiguella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 178: A method of controlling Crocidolomia binotalis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 179: A method of controlling representatives of the genus Cydia comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 180: A method of controlling Diparopsis castanea comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 181: A method of controlling representatives of the genus Earias comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 182: A method of controlling representatives of the genus Ephestia comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 183: A method of controlling representatives of the genus Heliothis of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 184: A method of controlling Hellula undalis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 185: A method of controlling Keiferia lycopersicella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 186: A method of controlling Leucoptera scitella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 187: A method of controlling representatives of the genus Lithocollethis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 188: A method of controlling Lobesia botrana comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 189: A method of controlling Ostrinia nubilalis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 190: A method of controlling representatives of the genus Pandemis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 191: A method of controlling Pectinophora gossypiella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 192: A method of controlling Phyllocnistis citrella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 193: A method of controlling representatives of the genus Pieris comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 194: A method of controlling Plutella xylostella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 195: A method of controlling representatives of the genus Scirpophaga comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 196: A method of controlling representatives of the genus Sesamia comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 197: A method of controlling representatives of the genus Sparganothis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 198: A method of controlling representatives of the genus Spodoptera comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 199: A method of controlling representatives of the genus Tortrix comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 200: A method of controlling Trichoplusia ni comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 201: A method of controlling representatives of the genus Agriotes comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 202: A method of controlling Anthonomus grandis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 203: A method of controlling representatives of the genus Curculio comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 204: A method of controlling Diabrotica balteata comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 205: A method of controlling representatives of the genus Leptinotarsa comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 206: A method of controlling representatives of the genus Lissorhoptrus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 207: A method of controlling representatives of the genus Otiorhynchus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 208: A method of controlling representatives of the genus Aleurothrixus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 209: A method of controlling representatives of the genus Aleyrodes comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 210: A method of controlling representatives of the genus Aonidiella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 211: A method of controlling representatives of the family Aphididae comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 212: A method of controlling representatives of the genus Aphis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 213: A method of controlling Bemisia tabaci comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 214: A method of controlling representatives of the genus Empoasca comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 215: A method of controlling representatives of the genus Mycus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 216: A method of controlling representatives of the genus Nephotettix comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 217: A method of controlling representatives of the genus Nilaparvata comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 218: A method of controlling representatives of the genus Pseudococcus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 219: A method of controlling representatives of the genus Psylla comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 220: A method of controlling representatives of the genus Quadraspidiotus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 221: A method of controlling representatives of the genus Schizaphis comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 222: A method of controlling representatives of the genus Trialeurodes comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 223: A method of controlling representatives of the genus Lyriomyza comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 224: A method of controlling representatives of the genus Oscinella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 225: A method of controlling representatives of the genus Phorbia comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 226: A method of controlling representatives of the genus Frankliniella comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 227: A method of controlling representatives of the genus Thrips comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 228: A method of controlling Scirtothrips aurantii comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 229: A method of controlling representatives of the genus Aceria comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 230: A method of controlling representatives of the genus Aculus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 231: A method of controlling representatives of the genus Brevipalpus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 232: A method of controlling representatives of the genus Panonychus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 233: A method of controlling representatives of the genus Phyllocoptruta comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 234: A method of controlling representatives of the genus Tetranychus comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 235: A method of controlling representatives of the genus Heterodera comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 236: A method of controlling representatives of the genus Meloidogyne comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Table 237: A method of controlling Mamestra brassica comprising the application of Spinosad to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to a line of the table C.

Example B1 Action Against Anthonomus grandis Adults, Spodoptera littoralis or Heliothis virescens

Young transgenic cotton plants which express the δ-endotoxin CryIIIA are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of emamectin-benzoate respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising emamectin-benzoate and conventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.

In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Example B2 Action Against Anthonomus grandis Adults, Spodoptera littoralis or Heliothis virescens

Young transgenic cotton plants which express the δ-endotoxin CryIIIA are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of abamectin respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising abamectin and conventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.

In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Example B3 Action Against Anthonomus grandis Adults, Spodoptera littoralis or Heliothis virescens

Young transgenic cotton plants which express the δ-endotoxin CryIIIA are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of spinosad respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising spinosad and conventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.

In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Example B4 Action Against Anthonomus grandis Adults, Spodoptera littoralis or Heliothis virescens

Young transgenic cotton plants which express the δ-endotoxin CryIa(c) are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of spinosad respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising spinosad and conventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.

In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Example B5 Action Against Anthonomus grandis Adults, Spodoptera littoralis or Heliothis virescens

Young transgenic cotton plants which express the δ-endotoxin CryIa(c) are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of abamectin respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising abamectin and conventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.

In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Example B6 Action Against Anthonomus grandis Adults, Spodoptera littoralis or Heliothis virescens

Young transgenic cotton plants which express the δ-endotoxin CryIa(c) are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of emamectin benzoate respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising emamectin benzoate and conventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.

In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Example B7 Action Against Ostrinia nubilalis, Spodoptera Spp. Or Heliothis Spp.

A plot (a) planted with maize cv. KnockOut® and an adjacent plot (b) of the same size which is planted with conventional maize, both showing natural infestation with Ostrinia nubilalis, Spodoptera spp. or Heliothis, are sprayed with an aqueous emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of spinosad. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of the endotoxin expressed by KnockOut®. Evaluation takes place 6 days later. The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis, Spodoptera spp. or Heliothis is observed on the plants of plot (a), while plot (b) shows a control level of not over 80%.

Example B8 Action Against Ostrinia nubilalis, Spodoptera Sp or Heliothis Sp

A plot (a) planted with maize cv. KnockOut® and an adjacent plot (b) of the same size which is planted with conventional maize, both showing natural infestation with Ostrinia nubilalis, Spodoptera sp or Heliothis, are sprayed with an aqueous emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of abamectin. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of the endotoxin expressed by KnockOut®. Evaluation takes place 6 days later. The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis, Spodoptera sp or Heliothis is observed on the plants of plot (a), while plot (b) shows a control level of not over 80%.

Example B9 Action Against Ostrinia nubilalis, Spodoptera Sp or Heliothis Sp

A plot (a) planted with maize cv. KnockOut® and an adjacent plot (b) of the same size which is planted with conventional maize, both showing natural infestation with Ostrinia nubilalis, Spodoptera sp or Heliothis, are sprayed with an aqueous emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of emamectin benzoate. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of the endotoxin expressed by KnockOut®. Evaluation takes place 6 days later. The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis, Spodoptera sp or Heliothis is observed on the plants of plot (a), while plot (b) shows a control level of not over 80%.

The invention further relates to

(B) A method of protecting plant propagation material and plant organs formed at a later point in time from attack by pests, characterized in that a pesticide comprising, as pesticidally active compound, at least one macrolide compound, especially abamectin, emamectin or spinosad in free form or in agrochemically utilizable salt form as active ingredient and at least one auxiliary in close spatial proximity to, or spatially together with, planting or applying the propagation material is employed to the site of planting or sowing; the corresponding use of these compounds, corresponding pesticides whose active ingredient is selected from amongst these compounds, a method of producing and using these compositions, and plant propagation material thus protected against attack by pests.

The macrolides used according to the invention are known to those skilled in the art. They are the classes of substances as mentioned under invention part (A). Abamectin and emamectin are preferred.

Agrochemically utilizable salts of the macrolides according to the invention are, for example, the same as under invention part (A).

In the case of abamectin, the free form is preferred in the frame of invention part (B). Especially preferred within the scope of the invention part (B) is a method in which emamectin is employed in free form or as agrochemically acceptable salt; especially as salt; in particular as the benzoate, substituted benzoate, benzenesulphonate, citrate, phosphate, tartrate or maleate; preferably as the benzoate or benzenesulphonate, especially preferably as the benzoate.

The scope of the subject-matter of the invention (B) extends in particular to representatives of the classes Insecta, Arachnida and Nematoda.

These are mainly insects of the order Lepidoptera, for example

Acleris spp., Adoxophyes spp., Aegeria spp., Agrotis spp., Alabama argillaceae, Amylois spp., Anticarsia gemmatalis, Archips spp., Argyrotaenia spp., Astylus atromaculatus, Autographa spp., Busseola fusca, Cadra cautella, Carposina nipponensis, Chilo spp., Choristoneura spp., Clysia ambiguella, Cnaphalocrocis spp., Cnephasia spp., Cochylis spp., Coleophora spp., Crocidolomia binotalis, Cryptophlebia leucotreta, Cydia spp., Diatraea spp., Diparopsis castanea, Earias spp., Ephestia spp., Eucosma spp., Eupoecilia ambiguella, Euproctis spp., Euxoa spp., Grapholita spp., Hedya nubiferana, Heliothis spp., Hellula undalis, Heteronychus arator, Hyphantria cunea, Keiferia lycopersicella, Leucoptera scitella, Lithocollethis spp., Lobesia botrana, Lymantria spp., Lyonetia spp., Malacosoma spp., Mamestra brassicae, Manduca sexta, Operophtera spp., Ostrinia nubilalis, Pammene spp., Pandemis spp., Panolis flammea, Pectinophora gossypiella, Phthorimaea operculella, Pieris rapae, Pieris spp., Plutella xylostella, Prays spp., Scirpophaga spp., Sesamia spp., Sparganothis spp., Spodoptera spp., Synanthedon spp., Thaumetopoea spp., Tortrix spp., Trichoplusia ni and Yponomeuta spp.; of the order Coleoptera, for example Agriotes spp., Anthonomus spp., Atomaria linearis, Chaetocnema tibialis, Cosmopolites spp., Curculio spp., Dermestes spp., Diabrotica spp., Epilachna spp., Eremnus spp., Leptinotarsa decemlineata, Lissorhoptrus spp., Melolontha spp., Orycaephilus spp., Otiorhynchus spp., Phlyctinus spp., Popillia spp., Psylliodes spp., Rhizopertha spp., Scarabeidae, Sitophilus spp., Sitotroga spp., Tenebrio spp., Tribolium spp. and Trogoderma spp.; of the order Orthoptera, for example Blatta spp., Blattella spp., Gryllotalpa spp., Leucophaea maderae, Locusta spp., Periplaneta spp. and Schistocerca spp.; of the order Psocoptera, for example Liposcelis spp.; of the order Anoplura, for example

Haematopinus spp., Linognathus spp., Pediculus spp., Pemphigus spp. and Phylloxera spp.;

of the order Mallophaga, for example Damalinea spp. and Trichodectes spp.; of the order Thysanoptera, for example Frankliniella spp., Hercinothrips spp., Taeniothrips spp., Thrips palmi, Thrips tabaci and Scirtothrips aurantii; of the order Heteroptera, for example Cimex spp., Distantiella theobroma, Dysdercus spp., Euchistus spp. Eurygaster spp. Leptocorisa spp., Nezara spp., Piesma spp., Rhodnius spp., Sahlbergella singularis, Scotinophara spp. and Triatoma spp.; of the order Homoptera, for example Aleurothrixus floccosus, Aleyrodes brassicae, Aonidiella spp., Aphididae, Aphis spp., Aspidiotus spp., Bemisia tabaci, Ceroplaster spp., Chrysomphalus aonidium, Chrysomphalus dictyospermi, Coccus hesperidum, Empoasca spp., Eriosoma larigerum, Erythroneura spp., Gascardia spp., Laodelphax spp., Lecanium corni, Lepidosaphes spp., Macrosiphus spp., Myzus spp., Nephotettix spp., Nilaparvata spp., Paratoria spp., Pemphigus spp., Planococcus spp., Pseudaulacaspis spp., Pseudococcus spp., Psylla spp., Pulvinaria aethiopica, Quadraspidiotus spp., Rhopalosiphum spp., Saissetia spp., Scaphoideus spp., Schizaphis spp., Sitobion spp., Trialeurodes vaporariorum, Trioza erytreae and Unaspis citri; of the order Hymenoptera, for example Acromyrmex, Atta spp., Cephus spp., Diprion spp., Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium pharaonis, Neodiprion spp., Solenopsis spp. and Vespa spp.; of the order Diptera, for example Aedes spp., Antherigona soccata, Bibio hortulanus, Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp., Cuterebra spp., Dacus spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Glossina spp., Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza spp., Musca spp., Oestrus spp., Orseolia spp., Oscinella frit, Pegomyia hyoscyami, Phorbia spp., Rhagoletis pomonella, Sciara spp., Stomoxys spp., Tabanus spp., Tannia spp. and Tipula spp.; of the order Siphonaptera, for example Ceratophyllus spp. and Xenopsylla cheopis; or of the order Thysanura, for example Lepisma saccharina.

Amongst the class Arachnida, they are preferably representatives of the order Acarina, for example

Acarus siro, Aceria sheldoni, Aculus schlechtendali, Amblyomma spp., Argas spp., Boophilus spp., Brevipalpus spp., Bryobia praetiosa, Calipitrimerus spp., Chorioptes spp., Dermanyssus gallinae, Eotetranychus carpini, Eriophyes spp., Hyalomma spp., Ixodes spp., Olygonychus pratensis, Ornithodoros spp., Panonychus spp., Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptes spp., Tarsonemus spp. and Tetranychus spp.

Especially preferred is the control of insects of the orders Coleoptera and Lepidoptera;

in the order Colepotera especially the genera and species Agriotes spp., Anthonomus spp., Atomaria linearis, Chaetocnema tibialis, Diabrotica spp. and Leptinotarsa decemlineata; in the order Lepidoptera the genera and species Adoxophyes spp., Agrotis spp., Alabama argillaceae, Anticarsia gemmatalis, Chilo spp., Cydia spp., Ephestia spp., Heliothis spp., Keiferia lycopersicella, Mamestra brassicae, Pectinophora gossypiella, Plutella xylostella, Sesamia spp., Spodoptera spp., Tortrix spp., and Trichoplusia.

A further preferred subject according to the invention part (B) is the control of representatives of the class Nematoda, such as root knot nematodes, stem eelworms and foliar nematodes;

especially Heterodera spp., for example Heterodera schachtii, Heterodora avenae and Heterodora trifolii; Globodera spp., for example Globodera rostochiensis; Meloidogyne spp., for example Meloidogyne incoginita and Meloidogyne javanica; Radopholus spp., for example Radopholus similis; Pratylenchus, for example Pratylenchus neglectans and Pratylenchus penetrans; Tylenchulus, for example Tylenchulus semipenetrans; Longidorus, Trichodorus, Xiphinema, Ditylenchus, Aphelenchoides and Anguina, in particular Meloidogyne, for example Meloidogyne incognita, and Heterodera, for example Heterodera glycines.

The macrolides used according to the invention (B) are preventatively and/or curatively valuable active ingredients in the fields of insect control, even at low application rates, while being well tolerated by warm-blooded species, fish, beneficials and plants. The active ingredients used according to the invention are effective against all or individual development stages of normally sensitive, but also resistant, pests. The action of the active ingredients used according to the invention may become apparent directly, i.e. in the form of destruction of the pests, which occurs immediately or only after some time has elapsed, for example during ecdysis, or indirectly, for example as a reduced oviposition and/or hatching rate, the good action corresponding to a destruction rate (mortality) of at least 50 to 60%.

With the aid of the active ingredients used in accordance with the invention part (B), it is possible to control, i.e. contain or destroy, pests which occur on plant propagation material, mainly on propagation material of useful plants and ornamentals in agriculture, in horticulture and in forests, and even plant organs which grow at a later point in time are still protected from these pests, that is to say the protection lasts, for example, until resistant mature plants have developed, and where the propagation material, or the plants developing therefrom, are protected not only from pests which attack the aerial plant organs, but also from soil-dwelling pests.

Suitable plant propagation material in the invention part (B), that is, for example, seedlings, rhizomes, nursery plants, cuttings or, in particular seed (seeds), such as fruit, tubers, kernels or bulbs, are, in particular, propagation material of cereals, such as wheat, barley, rye, oats, rice, maize or sorghum; beet, such as sugar or fodder beet; fruit, for example pome fruit, stone fruit and soft fruit, for example apples, pears, plums, peaches, almonds, cherries or berries, for example strawberries, raspberries and blackberries; legumes, such as beans, lentils, peas or soya beans, oil crops, such as oilseed rape, mustard, poppies, olives, sunflowers, coconut, castor-oil plants, cacao or peanuts; cucurbits, such as pumpkins, cucumbers or melons; fibre plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruit or mandarins; vegetables, such as spinach, lettuce, asparagus, cabbage species, carrots, onions, tomatoes, potatoes or capsicums; Lauraceae, such as avocado, Cinnamonium or camphor; or tobacco, nuts, coffee, egg plants, sugar cane, tea, pepper, grapevines, hops, Musaceae, latex plants or ornamentals;

especially of cereals, rice, cotton, maize, soya beans, oilseed rape, vegetables, potatoes, sunflowers, sugar beet and sorghum.

The genetically modified propagation material is preferably propagation material, in particular seed, which contains one or more genes expressing a pesticidal resistance, in particular an insecticidal or acaricidal, but also a fungicidal or nematocidal, resistance, which make the plant resistant to herbicides, which lead to increased resistance to plant diseases or which introduce other agronomically advantageous properties into the plant. Such plants, or their propagation material, are in particular those which contain a gene derived from a Bacillus thuringiensis and which encode an insecticidally active protein or contain a gene. These are, especially, genetically modified plant propagation materials of potatoes, alfalfa, cereals, such as wheat, barley, rye, oats, rice, maize or sorghum; legumes, such as beans, lentils, peas or soya beans; beet such as sugar or fodder beet; oil crops, such as oilseed rape, mustard, poppies, olives, sunflowers, coconut, castor-oil plant, cacao or peanuts; cucurbits, such as pumpkins, cucumbers or melons; fibre plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruit or mandarins; vegetables, such as spinach, lettuce, asparagus, cabbage species, carrots, onions or tomatoes.

Examples of the genetically modified plant propagation material mentioned are, for example, the commercially available products Maximizer® (KnockOut®), Yieldgard®, Roundup Ready Soybeans®, TC Blend® or NuCOTN 33B®, all of which are known to those skilled in the art.

Other fields of application for the active ingredients used in accordance with the invention part (B) are, for example, the protection of stored products or stores or in the hygiene sector; in particular the protection of domestic animals or productive livestock from pests.

The invention of subject-matter (B) therefore also relates to corresponding pesticides for use, to be selected depending on the intended aims and the prevailing circumstances, such as emulsifiable concentrates, suspension concentrates, directly sprayable or dilutable solutions, spreadable pastes, dilute emulsions, sprayable powders, soluble powders, dispersible powders, wettable powders, dusts, granules or encapsulations in polymeric substances which comprise—at least—one of the active ingredients used in accordance with the invention, and to the use of these insecticidal compositions for use in a method. Preferred is a composition which comprises only one macrolide compound, especially emamectin or a salt thereof.

In these compositions, the active ingredient is employed in pure form, for example a solid active ingredient in a particular particle size or, preferably, together with—at least—one of the auxiliaries conventionally used in the art of formulation, such as extenders, for example solvents or solid carriers, or such as surface-active compounds (surfactants).

Suitable auxiliaries such as solvents, solid carriers, surface-active compounds, non-ionic surfactants, cationic surfactants and anionic surfactants in the compositions employed in accordance with the invention are, for example, those which have been described in EP-A-736 252.

Liquid formulations for the treatment of plant propagation material according to invention part (B), especially of seed, comprise, for example,

surface-active substances (1-15% by weight), such as ethoxylated tristyrenephenols and their salts, alkyl polyglycol ether ethoxylates, polyoxypropylene/polyoxyethylene copolymers, the sodium salt of lignosulphonic acid, salts of polynaphthalenesulphonic acid and alkylbenzenesulphonic acid triethanolamine salt; antifreeze agents (5-15%), such as, for example, DL-propane-1,2-diol or propane-1,2,3-triol; colourants (1-10%), such as pigments or water-soluble dyes; antifoams (0.05-1%), such as polydimethylsiloxane; coatings (1-10%), such as polyethylene glycol, polyvinyl acetate, polyvinylpyrrolidone, polyacrylate; preservatives (0.1-1%), such as 1,2-benzoisothiazol-3-one; thickeners (0.1-1%), such as heteropolysaccharide; and solvents, such as water.

Solid formulations for the treatment of plant propagation material, especially of seed, comprise, for example:

surface-active substances (1-10%), such as alkyl polyglycol ether ethoxylate, polyoxypropylene/polyoxyethylene copolymers, the sodium salt of lignosulphonic acid, salts of polynaphthalenesulphonic acid; colourants (1-10%), such as pigments or water-soluble dyes; antifoams (0.05-1%), such as polydimethylsiloxane; coatings (1-10%), such as polyethylene glycol or cellulose; and carriers (to 100% w/w), such as silica powder, talc powder, clays and the like.

As a rule, the compositions comprise 0.1 to 99%, in particular 0.1 to 95%, of active ingredient and 1 to 99.9%, in particular 5 to 99.9%, of—at least—one solid or liquid auxiliary, it being possible, as a rule, for 0 to 25%, in particular 0.1 to 20%, of the compositions to be surfactants (% is in each case percent by weight). While concentrated compositions are more preferred as commercially available goods, the end consumer will use, as a rule, dilute compositions having much lower concentrations of active ingredient.

Preferred compositions, such as emulsifiable concentrations, dusts, suspension concentrates, wettable powders and granules have, for example, those compositions which are mentioned in EP-A-736 252.

The compositions according to the invention part (B) can also comprise other solid or liquid auxiliaries, such as stabilizers, for example unepoxidized or epoxidized vegetable oils (for example epoxidized coconut oil, rapeseed oil or soya oil), antifoams, for example silicone oil, preservatives, viscosity regulators, binders and/or tackifiers, and also fertilizers or other active ingredients for achieving specific effects, for example bactericides, nematicides, molluscides or selective herbicides.

The action of the compositions according to the invention part (B) can be broadened considerably by adding other, for example insecticidally, acaricidally and/or fungicidally active, ingredients and adapted to prevailing circumstances. Suitable additions of insecticidally and acaricidally active ingredients are, for example, representatives of the following classes of active ingredients: organophosphorus compounds, nitrophenols and derivatives, formamidines, triazine derivatives, nitroenamine derivatives, nitro- and cyanoguanidine derivatives, ureas, benzoylureas, carbamates, pyrethroids, chlorinated hydrocarbons and Bacillus thuringiensis products. Especially preferred components in mixtures are NI-25, TI-304, TI-435, MTI-446, fipronil, lufenuron, pyripfoxyfen, thiacloprid, fluxofenime; imidacloprid, thiamethoxam, fenoxycarb, diafenthiuron, pymetrozine, diazinon, disulphoton; profenofos, furathiocarb, cyromazin, cypermethrin, tau-fluvalinate, tefluthrin or Bacillus thuringiensis products, very especially NI-25, TI-304, TI-435, MTI-446, fipronil, thiacloprid, imidacloprid, thiamethoxam and tefluthrin.

Examples of suitable additions of fungicidally active ingredients are the following compounds: azoxystrobin; bitertanol; carboxin; Cu₂O; cymoxanil; cyproconazole; cyprodinil; dichlofluamid; difenoconazole; diniconazole; epoxiconazole; fenpiclonil; fludioxonil; fluquiconazole; flusilazole; flutriafol; furalaxyl; guazatin; hexaconazole; hymexazol; imazalil; imibenconazole; ipconazole; kresoxim-methyl; mancozeb; metalaxyl; R-metalaxyl; metconazole; oxadixyl, pefurazoate; penconazole; pencycuron; prochloraz; propiconazole; pyroquilone; SSF-109; spiroxamin; tebuconazole; teflutrin; thiabendazole; tolifluamide; triazoxide; triadimefon; triadimenol; triflumizole; triticonazole and uniconazole.

The compositions to be used according to the invention part (B) are prepared in a known manner, for example in the absence of auxiliaries by grinding and/or screening, for example to a particular particle size, or by compressing a solid active ingredient, and in the presence of at least one auxiliary, for example by intimately mixing and/or grinding the active ingredient with the auxiliary/auxiliaries. These methods for preparing the compositions according to the invention and the use of macrolides for preparing these compositions are also subjects of the invention.

The application methods according to the invention part (B) for the protection of plant propagation material, which, in accordance with the invention, is any plant material capable of developing complete plants after planting or sowing to the site of planting or sowing, for example seedlings, rhizomes, nursery plants, cuttings or, in particular, seed (seeds), such as fruits, tubers, kernels or bulbs, against attack by pests are characterized in that, for example, suitable compositions are applied in such a manner that they are applied in close spatial proximity to, or spatially together with, planting or sowing the propagation material to the site of planting or sowing. Application of these compositions in close spatial proximity to planting or sowing the propagation material to the site of planting or sowing takes place in accordance with the invention, preferably prior to planting or sowing the propagation material, by applying the compositions by soil application directly to the site where the propagation material has been planted or sown, for example preferably prior to sowing into the seed furrow or to a closely delimited area around the site of planting or sowing the propagation material. Application of such compositions, which takes place spatially together with planting or applying the propagation material to the site of planting or sowing is to be understood as meaning that propagation material which has been pretreated with these compositions is planted or sown at the site of planting or sowing, it being possible, depending on the intended aims and prevailing circumstances, for the pretreatment of the propagation material to be effected for example by spraying, atomizing, dusting or scattering the compositions over the propagation material or brushing or pouring the compositions over the propagation material or, in the event of seed, in particular also by dressing the seed. When carrying out seed dressing, which is preferred according to the invention, i.e. dry seed, wet seed-dressing, liquid seed-dressing or slurry dressing, a suitable pesticide is added to the seed prior to sowing in a seed-dressing apparatus and the composition is distributed uniformly over the seed, for example by stirring the contents of the seed-dressing apparatus and/or by rotating and/or shaking the entire seed-dressing apparatus. Particular embodiments of such a seed-dressing treatment comprise, for example, immersing the seed in a liquid composition, coating the seed with a solid composition (seed coating) or by achieving penetration of the active ingredient into the seed by adding the composition to the water used for pre-soaking the seed (seed soaking). Typical application rates for the compositions used in the seed-dressing treatment according to the invention are, for example, between 0.1 and 100 g of active ingredient per 100 kg of seed, in particular between 1 and 60 g/100 kg of seed, preferably between 4 and 40 g/100 kg of seed.

The seed-dressing treatment according to invention part (B) comprises, in particular, that due to the low toxicity of the active ingredient used, good tolerance by birds of the dressed seed is observed, for example, in the case of birds which, being seed-eaters in the open countryside, tend to take seed from freshly seeded fields, such as buntings, blackbirds, thrushes, ducks, pheasants, finches, geese, linnets, chickens, crows, skylarks, tits, seagulls, ravens, partridges, wood pigeons, goldfinches, pigeons or siskins. The seed-dressing treatment according to the invention also extends to the dressing of stored seed.

The commercial plant propagation material which has been pretreated according to invention part (B) is another subject of the invention.

Examples of formulations of macrolide compounds which can be used in the method according to the invention (B), that is to say solutions, granules, dusts, sprayable powders, emulsion concentrates, coated granules and suspension concentrates, are of the type as has been described in, for example, EP-A-580 553, Examples F1 to F10.

Example F1 General Procedure for Liquid Seed Dressing

The required amount of liquid formulation is placed into an Erlenmeyer flask. The flask is shaken to distribute the liquid on the entire bottom of the vessel. The required amount of seed is introduced into the flask immediately thereafter. The flask is shaken vigorously by hand for approximately one minute so that all the seed is covered with liquid. The contents of the flask are turned out onto a drying rack and dried in an oven.

Example F2 General Procedure for Dry Seed Dressing

Various wide-necked flasks are each filled with the same number of seed kernels, and each flask is charged with such an amount of wettable powder that the desired amount of active ingredient per seed kernel (for example 0.03, 0.1 or 0.3 mg per kernel) is obtained. The flasks are placed on a roller and rotated for three minutes at 80 rotations/minute. The seed kernels which are attached to the walls of the flasks are then disengaged by shaking by hand, and the flasks are rotated in the opposite direction for three minutes.

BIOLOGICAL EXAMPLES %=Percent by Weight, Unless Otherwise Specified Example B4 Seed-Dressing Action Against First-Instar Larvae of Spodoptera littoralis on Maize Leaves

Maize seeds which have been dressed as described in procedure F1 are sown. 12, 19, 26, 33, 40 and 47 days after sowing, sections 5 to 8 cm in length of the top-most leaves of the plants are placed in glass beakers and infested with a predetermined quantity of a suspension of freshly hatched L1 larvae of Spodoptera littoralis. The beakers are closed with a lid and kept at 25° C., a relative atmospheric humidity of 60% and a day-light cycle of 16 hours. Evaluation takes place three to five days after infestation. The percentage reduction in population (% action) is determined by comparing the number of surviving larvae on the plants grown from dressed seeds and from untreated seeds.

Example B5 Seed-Dressing Action Against Adult Diabrotica balteata on Sugar Beet Leaves

Seeds of sugar beet which have been dressed as described in procedure F1 are sown. 33, 40, 47, 54 and 61 days after sowing, the leaves of in each case three to 5 plants are placed in a glass beaker and infested with a predetermined number of young adult Diabrotica balteata. The beakers are closed with a lid and kept at 25° C., a relative atmospheric humidity of 60% and 16 hours of daylight. Evaluation takes place three to five days after infestation. The percentage reduction in population (% action) is determined by comparing the number of surviving Diabrotica adults on the plants grown from dressed seeds and from untreated seeds.

Example B6 Seed-Dressing Action Against Third-Instar Larvae of Diabrotica balteata on Maize Roots

Maize seeds which have been treated as described in procedure F1 are sown. 14, 21 and 28 days after sowing, in each case five third-instar larvae of Diabrotica balteata are placed on the bottom of each plant pot. Evaluation takes place 6 days after infestation. The data registered are the number of surviving instars (larvae and pupae) in the stem of the plants, on the soil surface and in the soil. The percentage reduction in population (% action) is determined by comparing the number of surviving larvae and pupae on the plants grown from dressed seeds and from untreated seeds and their environment.

Example B7 Seed-Dressing Action Against Aphis fabae

A glass flask or a plastic container is filled with 100 g of bean seeds and such an amount of a formulation of the active ingredient that a ratio of 0.1, 1 or 10 g of active ingredient per kg of seed is achieved. The active ingredient is distributed uniformly on the seed surface by rotating and/or shaking the container. The seeds which have been dressed in this way are sown in flowerpots (3 seeds per pot). The plantlets are grown in a greenhouse at 25 to 30° C. until they have reached the 2-leaf stage and then populated with Aphis fabae. 6 days after population, the test is evaluated. The percentage reduction in population (% action) is determined by comparing the number of surviving individuals on the plants grown from dressed seeds and from untreated seeds.

In this test, a good action is shown by abamectin, emamectin and spinosad.

Example B8 Seed-Dressing Action Against Myzus persicae

A glass flask or a plastic container is filled with 100 g of sugar beet seeds and such an amount of a pasty formulation of the active ingredient, prepared with a sprayable powder and a little water, that a ratio of 0.1, 1 or 10 g of active ingredient per kg of seed is achieved. The closed seed-dressing container is agitated on a roller until the paste is distributed uniformly on the seed surface. The seeds which have been dressed (coated) in this way are dried and sown into loess soil in plastic pots. The seedlings are grown in a greenhouse at 24 to 26° C., a relative atmospheric humidity of 50 to 60% and a daily illumination time of 14 hours. 4 weeks after germination, the plants, which are 10 cm high, are populated with a mixed population of Myzus persicae. Evaluation takes place 2 and 7 days after the plants have been populated. The percentage reduction in population (% action) is determined by comparing the number of surviving individuals on the plants grown from dressed seeds and from untreated seeds.

In this test, a good action is shown by abamectin, emamectin and spinosad.

The invention further relates to

(C) A method of controlling wood pests and molluscs, characterized in that a pesticidally active amount of a pesticide comprising, as pesticidally active compound, at least one macrolide, preferably abamectin, emamectin or spinosad, in free form or agrochemically utilizable salt form, as active ingredient and at least one auxiliary is applied to the pests or their environment; to the corresponding use of these compounds, to corresponding pesticides whose active ingredient is selected from amongst these compounds, to a process for the preparation of and to the use of these compositions, and to plant propagation material thus protected from attack by pests.

The macrolides used in accordance with the invention are the same as mentioned under the aspect (A) of the invention. Also the salt are as mentioned under invention part (A). In the case of abamectin, the free form is preferred in accordance with the invention. Especially preferred for the purposes of the present invention is a composition which comprises emamectin in free form or as an agrochemically tolerated salt as the only pesticidally active component; especially as the salt; more especially as the benzoate, substituted benzoate, benzenesulphonate, citrate, phosphate, tartrate or maleate; preferably as the benzoate or benzenesulphonate, especially preferably as the benzoate.

A larger number of different classes of active ingredient are mentioned in the literature as arthropodecidally acting active ingredients for controlling gastropods and termites. Surprisingly, it has now been found that the compounds known under the collective term macrolides, too, exhibit an important molluscicidal and termiticidal activity, specifically against gastropods, such as slugs and snails, and against wood pests, in particular representatives of the order of Isoptera.

The molluscs include, for example,

Ampullariidae; Arion (A. ater, A. circumscriptus, A. hortensis, A. rufus); Bradybaenidae (Bradybaena fruticum); Cepaea (C. hortensis, C. Nemoralis); Cochlodina; Deroceras (D. agrestis, D. empiricorum, D. laeve, D. reticulatum); Discus (D. rotundatus); Euomphalia; Galba (G. trunculata); Helicella (H. itala, H. obvia); Helicidae (Helicigona arbustorum); Helicodiscus; Helix (H. aperta); Limax (L. cinereoniger, L. flavus, L. marginatus, L. maximus, L. tenellus); Lymnaea; Milax (M. gagates, M. marginatus, M. sowerbyi); Opeas; Pomacea (P. canaticulata); Vallonia and Zanitoides.

The termites include, in particular, the families Hodotermitidae, Kalotermitidae, Rhinotermitidae and Termitidae. Other pests which damage wood by feeding on wood, using it as a substrate or reproducing on wood, are to be understood as meaning, for example, wood-boring insects such as representatives of the family Lyctidae, the family Apidae, for example Xylocopa virginica, and of the family Anobiidae, such as Anobium punctatum.

Slugs and snails as pests in horticulture and agriculture are a massively increasing problem. They can cause severe plant damage by feeding, and can also bring about undesirable soiling by slug and snail mucus and faeces. Novel changes in the management of crops have led to an increased number in varieties of plant species which are sensitive to slugs and snails, and the obligation to dispense with burning stubble fields—which is based on an ecological approach—and to plough in the straw instead suggests that the existing mollusc problems, especially slug problems, will be made worse.

Termites are capable of inflicting substantial damage to buildings in particular at geographical latitudes of between 42° N and 42 S°. In principle, two types of termites can be distinguished:

Termites which live in the subsoil—the most widely distributed type—require warm air and a moist environment. In order always to have available the necessary moisture, these termites must have direct access to the moist soil. Damage caused by subterranean termites is virtually always associated with damage to wood.

Termites which use dry wood as their substrate represent—even though less frequently—a large problem since they do not require contact with the moist soil. They penetrate into buildings underneath roof shingles, through gaps and through ventilation holes. Others are brought into households with items of furniture which are already infested. Pretreatment of the wood is considered the most efficient method of controlling such termites. The damages of termites living on dry wood are caused more slowly than damages of termites living in a moist environment, therefore, damage caused by termites of the first-mentioned type is found predominantly in old buildings.

Damage caused by termites living subterraneously in a humid environment can be prevented by the application of insecticidally active substances to the termites or their environment. Such compounds are conventionally employed mainly for application to the soil around the buildings.

Gastropodicides which are currently commercially available comprise metaldehyde and carbamates such as, for example, methiocarb. Carbamates are highly effective as molluscicides, but exhibit the serious disadvantage of being highly toxic to mammals such as, for example, cats, dogs and hedgehogs, and other organisms such as, for example, earthworms, which should be left unharmed. While the metaldehyde molluscicides exhibit a lower toxicity, they are not lethal to molluscs but have an anaestheticizing or dehydrating effect, thus immobilizing the pests. There is therefore a demand for a useful molluscicide which is highly effective against, for example, slugs and snails, but has no, or a very low, toxic effect on beneficials such as, for example, earthworms, and mammals. This object is achieved with the macrolides of the present invention.

Also, the currently available compositions for controlling termites are not satisfactory in all respects since generally relatively large zones around building constructions, or these buildings themselves, must be treated with large amounts of insecticide. This can lead to secondary problems, in particular in the case of persistent pesticides, especially in houses. Here too, there is therefore a further demand for improved solutions, in particular by applying active ingredients which can be employed in particularly low quantities and which have low volatility.

The invention part (C) therefore also relates to pesticides such as emulsifiable concentrates, suspension concentrates, directly sprayable or dilutable solutions, spreadable pastes, dilute emulsions, sprayable powders, soluble powders, dispersible powders, wettable powders, dusts, granules, pellets or encapsulations in polymeric substances, all of which are to be chosen to suit the intended aims and the prevailing circumstances and which comprise—at least—one of the active ingredients according to the invention.

The active ingredient is employed in these compositions in pure form, for example a solid active ingredient in a particular particle size, or, preferably, together with—at least—one of the auxiliaries or carriers conventionally used in formulation technology.

Examples of formulation auxiliaries are solid carriers, solvents, stabilizers, slow-release auxiliaries, colorants and, if appropriate, surface-active substances (surfactants). Suitable carriers and auxiliaries are all substances conventionally used in crop protection products, in particular in gastropodicides. Suitable auxiliaries such as solvents, solid carriers, surface-active compounds, non-ionic surfactants, cationic surfactants, anionic surfactants and other auxiliaries in the compositions employed in accordance with the invention are, for example, those which have been described in EP-A-736,252.

Other suitable substances which can be used as carriers for molluscicides are phagostimulants, that is to say the attractants and/or food (that is to say substances which can be utilized physiologically by slugs and snails) usually contained in slug and snail bait formulations. Mixtures of phagostimulants with other suitable organic and/or inorganic carriers may also be used.

Suitable phagostimulants for molluscicides are preferably: ground cereals, such as, for example, wheat flour, barley flour, rye flour, and also rice starch, crushed soya beans, fish meal, molasses, crushed rapeseed and the like. It is possible to employ either only one phagostimulant or else a mixture of phagostimulants.

To make the bait more palatable for the molluscs, one or more of the following substances can be used as additive for slug and snail baits:

a) a vitamin B, in particular B1, B2, nicotinic acid or nicotinamide; b) vitamin E; c) animal or vegetable proteinaceous material, for example albumins and their hydrolytic degradation products, in particular those obtained by enzymatic hydrolysis by, for example, pepsin, such as metaproteins, proteoses, peptones, polypeptides, peptides, diketopiperazines and amino acids; d) one or more amino acids or salts or amides thereof, which may also be synthetic products; e) a nucleic acid or a hydrolytic degradation product thereof, such as a nucleotide, a nucleoside, adenine, guanine, cytosine, uracile or thymine; f) urea, carbamic acid; g) an ammonium salt, for example ammonium acetate; h) an amino sugar, for example, glucosamine or galactosamine; i) compounds of sodium, potassium, calcium or magnesium, or traces of compounds of manganese, copper, iron, cobalt, zinc, aluminium, boron or molybdenum, in particular chelates of these, such as Versene®; j) phosphoric acid, or glyceryl or sugar phosphates; k) water.

Stabilizers may be all known food stabilizers which have a fungistatic, fungicidal, bacteriostatic and/or bactericidal action, such as sodium benzoate, methyl p-hydroxy-benzoate, cetyltrimethylammonium bromide, citric acid, tartaric acid, sorbic acid, phenols, alkylphenols or chlorinated phenols.

Slow-release auxiliaries which may be employed include, in addition to the substances mentioned as solid carriers, resins such as urea/formaldehyde resins, soya-bean meal, waxes, stearates and oils such as castor oil.

Substances which can be employed as auxiliaries for molluscicides according to part (C) of the invention are, for example, binders such as methylcellosolve, polyvinylpyrrolidone, polyvinyl alcohol, polyacrylates, polymethacrylates, natural waxes, chemically modified waxes and synthetic waxes, sugars, starch, alginates, agar, lignosulphonates and gum arabic, humectants such as polyalcohols, for example sugars or glycerol, preservatives, colorants, snail and slug attractants, repellents for warm-blooded species and/or other formulation auxiliaries. Combinations with known molluscicidally active ingredients, for example metaldehyde or mercaptodimethur, are also possible.

The formulation steps can be complemented by kneading, granulating (granules) and, if appropriate, compressing (pills, tablets, pellets).

The molluscicidal compositions which preferably comprise, other carriers and/or auxiliaries in addition to the active ingredient are preferably present in the ready-to-use form as sprayable powders, tracking powders, as granules (the active ingredient being present as a mixture with the carrier material), or as pellets. Especially preferred formulations are tracking powders, granules or pellets.

Formulations which are specifically suitable for controlling molluscs according to part (C) of the invention are granules or pellets which comprise, as a rule, 0 to 90%, preferably 0 to 70%, of carrier material, 0.1 to 10%, preferably 1 to 5%, of active ingredient, 10 to 95%, preferably 25 to 90%, of phagostimulant, 0.5 to 25%, preferably 5 to 20%, of binder and, if appropriate, 0 to 15% of other auxiliaries (% is in each case percent by weight).

The amount to be applied in each case as gastropodicide is not critical, due to the lack of, or low, toxicity to warm-blooded species and depends on the prevailing circumstances, such as severity of infestation, climatic conditions and the plants to be protected. The application rate of bait types according to the invention can be varied within a substantial range. In general, between 3 and 15 kg of snail and slug bait are used per hectare, preferably between 5 and 10 kg per hectare. Expediently, the gastropodicides are distributed as uniformly as possible between the crop plants by spraying an aqueous suspension or by spreading the powders, granules or pellets on the soil. If the plant canopy is not dense, it may also be expedient to establish “trapping strips” around the plants to be protected.

Since the gastropodicides according to the invention are outstandingly well tolerated by plants, no limitations apply to the plants to be protected. Thus, all ornamentals and crop plants in agriculture, forests and horticulture (also in greenhouses) in all growth stages can be protected from slug and snail damage.

The formulation and the use of the slug and snail baits according to the invention and of the compositions for controlling wood pests can be seen from the examples which follow.

The compositions to be used according to the invention part (C) for controlling gastropods and wood pests are prepared in the known manner, in the absence of auxiliaries for example by grinding and/or straining, for example to obtain a particular particle size, or by compressing a solid active ingredient, and in the presence of at least one auxiliary for example by intimately mixing and/or grinding the active ingredient with the auxiliary/auxiliaries. These processes for the preparation of the compositions according to the invention and the use of the macrolides for the preparation of these compositions are also the subject of the invention.

As a rule, the compositions in the frame of part (C) of the invention comprise 0.1 to 99%, in particular 0.1 to 95%, of active ingredient and 1 to 99.9%, in particular 5 to 99.9%, of—at least—one solid or liquid auxiliary, it being possible, as a rule, for surfactants to account for 0 to 25%, in particular 0.1 to 20%, of the compositions (% is in each case percent by weight). While concentrated compositions are more preferred as commercially available goods, the consumer uses, as a rule, dilute compositions which have much lower concentrations of active ingredient.

The activity of the compositions according to the invention can be widened considerably by adding other, for example insecticidally, acaricidally and/or fungicidally active ingredients and adapted to the prevailing circumstances. Examples of suitable added active ingredients are the same as mentioned under part (B) of the invention.

In an especially preferred embodiment of the invention, the macrolide compound is used for controlling the termites and other wood-destroying pests in the soil, thus achieving an in-direct protection of timber constructions. An amount of the macrolide sufficient to control the pests is applied to the soil, preferably at an application rate of 1 g to 2000 g per hectare, especially 2 to 200 g, in particular 5 to 100 g.

Worker termites must work on the pesticide-treated soil to gain access to the wood. Inevitably, they will take up some of the pesticide and carry it back to the termite colony and thus spread the active ingredient in the termite colony.

The active ingredient(s) can also be applied in the form of baits, for example in the form of tablets which comprise the active ingredient, such as are described in U.S. Pat. No. 5,096,710. Especially preferably, the macrolide is applied to materials which are used by the termites as food and building materials for the termite colony. Examples of such materials are board, paper, wood dust, cellulose powder or cotton. Useful concentrations on these materials are 0.01 to 10,000 ppm. Such baits are especially efficient even when pheromones are additionally employed and wood is used which has already been attacked by fungi. Such uses are discussed, for example, in in U.S. Pat. No. 5,151,443.

The macrolides according to the invention part (C) are preventatively and/or curatively valuable active ingredients with a very favourable biocidal spectrum in the field of mollusc and wood-pest control, even at low use concentrations, and are well tolerated by warm-blooded species, fish and plants. The active ingredients according to the invention are active against all or individual developmental stages of normally sensitive, but also resistant, molluscs and wood pests, especially termites. The molluscicidal action of the active ingredients according to the invention may manifest itself directly, i.e. in destruction of the pests, either immediately or only after some time has elapsed, or indirectly, for example in a reduced oviposition and/or hatching rate, the good action corresponding to a destruction rate (mortality) of at least 50 to 60%.

Using the active ingredients according to the invention part (C), it is possible to control, i.e. contain or destroy, mollusc damage in particular on plants, mainly on useful plants and ornamentals in agriculture, in horticulture and in forests, or pests of the abovementioned type which occur on organs of such plants, such as fruits, flowers, foliage, stalks, tubers or roots and in some cases even plant organs which grow at a later point in time are still protected from these pests.

Suitable target crops for mollusc control are, in particular, cereals, such as wheat, barley, rye, oats, rice, maize or sorghum; beet, such as sugar or fodder beet; fruit, for example pome fruit, stone fruit and soft fruit, such as apples, pears, plums, peaches, almonds, cherries or berries, for example strawberries, raspberries or blackberries; legumes such as beans, lentils, peas or soya beans; oil crops such as oil seed rape, mustard, poppies, olives, sunflowers, coconuts, castor, cacao or peanuts; the marrow family, such as pumpkins, cucumbers or melons; fibre plants such as cotton, flax, hemp or jute; citrus fruits such as oranges, lemons, grapefruits or tangerines; vegetables such as spinach, lettuce, asparagus, cabbage species, carrots, onions, tomatoes, potatoes, or capsicums; the laurel family such as avocado, Cinnamonium or camphor; and tobacco, nuts, coffee, egg plants, sugar cane, tea, pepper, grapevines, hops, the banana family, latex plants and ornamentals.

Other fields of application for the active ingredients according to the invention part (C) are the protection of stored products and stores and of materials from molluscs and wood pests.

The compositions according to the invention part (C) are also suitable for the protection of plant propagation material, for example seed, such as fruits, tubers or kernels, or plant propagules, from gastropods and termites, especially gastropods. The propagation material can be treated with the composition prior to planting, for example seed prior to sowing. Alternatively, the active ingredients according to the invention can be applied to seed kernels (coating) either by soaking the kernels in a liquid composition or by coating them with a solid composition. Alternatively, the composition can be applied to the site of planting when the propagation material is being planted, for example into the seed furrow during sowing. These treatment methods for plant propagation material and the plant propagation material treated thus are further subjects of the invention.

The examples which follow are intended to illustrate part (C) of the invention. They do not impose any limitation thereto.

FORMULATION EXAMPLES Example F3 Preparation of Slug Pellets

40 kg of crushed rapeseed (ratio of extracted/non-extracted crushed rapeseed=65:35), 2.6 kg of a finely ground premix comprising 2.1 kg of macrolide and 500 g of highly-disperse silica, 4.7 kg of cold crosslinked cornstarch, 540 g of urea/formaldehyde resin, 100 g of isopropanol, 3 kg of sugar beet molasses and 140 g of blue colorant (1,4-di(isobutylamino)anthraquinone) are introduced in succession into a mixer and mixed intimately. This is followed by compression moulding. The product is left to cool and dry, and fines are removed using a 0.5 mm screen. This gives a ready-to-use slug and snail bait formulation.

Instead of the abovementioned compression moulding method, another, customary compacting method may also be used for preparing the slug and snail bait formulation.

USE EXAMPLES Example A1 Test for Determining the Efficacy of Slug and Snail Pellets Against Deroceras reticulatum

The efficacy of slug and snail pellets against small slug species, for example Deroceras species, is tested in polycarbonate boxes with a 17 cm×22 cm base. The bottom of the box is covered with several layers of cellulose paper which is moistened sufficiently. The slug and snail pellets are scattered uniformly over one half of the test area at an application rate of 20 particles; the other half remains untreated. To avoid forced behaviour, the slugs are additionally given untreated supplementary feed: two potato halves arranged in diagonally opposite corners of the box. 10 adult reticulated field slugs (Deroceras reticulatum) are introduced to the untreated area of each box. Each test is replicated three times. Temperature and atmospheric humidity are kept virtually constant during the entire test period: 19° and 90 to 95% relative atmospheric humidity. The state of the slugs is checked and scored daily on seven consecutive days. When assessing the efficacy, the mortality rate and the number of animals which show symptoms of damage are taken into consideration.

In this test, the macrolides according to the invention are very effective.

Example A2 Test for Determining the Efficacy of Slug and Snail Pellets Against Arion rufus

The efficacy of slug and snail pellets against larger slug species is tested in plastic test boxes equipped with a wire mesh. Each box has a base of 0.25 m². The bottom of the box is covered by a 2 to 3 cm deep layer of potting compost. The potting compost is moistened sufficiently before the beginning of the experiment. Slug and snail pellets are scattered uniformly over the left half of the experimental area at an application rate of 3.1 g; the right half remains untreated. To avoid forced behaviour, the slugs are additionally given untreated supplementary feed: two potato halves arranged in diagonally opposite corners of the box. 10 adult red slugs (Arion rugus) are introduced to the untreated area of each box. Each test is replicated four times. Temperature and atmospheric humidity are kept virtually constant during the entire test period: 19° and 90 to 95% relative atmospheric humidity. The state of the slugs is checked and scored daily on seven consecutive days. When assessing the efficacy, the mortality rate and the number of animals which show symptoms of damage are taken into consideration.

In this test, the macrolides according to the invention are very effective.

Example A3 Test for Determining Systemic Efficacy Against Deroceras reticulatum a) Lettuce Plants

A test solution is prepared by dissolving a macrolide sample in 1 ml of acetone and making up the solution with water to 50 ml. The roots, previously cleaned with fresh water, of young lettuce plants 6 cm in height are immersed for at least two days in this solution. For each test, individual leaves are excised from these lettuce plants and placed on a paper filter in a 9 cm Petri dish. 1 ml of water is pipetted onto each paper filter to keep the leaves moist during the experiment. Then, two medium-sized slugs are introduced into each Petri dish and the amount of consumed leaves and the mortality is determined over a period of two days.

In this test, the macrolides according to the invention show a good action.

b) Seed

Batches of 10 slugs are introduced into 5 sealed boxes containing compost and having a base of 35 cm×20 cm. In each case 100 treated winter wheat kernels are scattered uniformly into four boxes. In the fifth box, 50 treated winter wheat kernels are distributed over one side of the box and 50 untreated winter wheat kernels over the other side of the box to test the repellent action.

In this test, the macrolides according to the invention are very effective.

Example A4 Action Against Termites

Wood baits are treated with different amounts of macrolide, and their effect on hatching rate and survival of termites is tested. Solutions with concentrations of 0 ppm, 0.1 ppm, 100 ppm and 1000 ppm of the test substance in acetone are used. Water is used in the control study. The baits consist of pine wood which have been kept in a natural environment for four months.

The termites are collected from infested pieces of wood in the open. To carry out the wood bait study, the wood is kept for 48 hours in an oven at 80° C. The dried wood is then weighed, and the pieces are placed for 18 hours in solutions of the active ingredient at the desired concentration. The pieces of wood are then removed from the solutions, dried in the air and reweighed. To determine the action of the baits against termites, the pieces of wood thus treated are placed on a thin layer of untreated soil in Petri dishes.

The termites (50 workers and 2 soldiers) are introduced into each Petri dish. The dishes are inspected three times per week, over a period of 8 weeks. Insect development, abnormalities and mortalities are recorded. After 8 weeks, the logs are rinsed with water and dried again in an oven for 48 hours at 80° C. Again, the weight of each piece of wood is subsequently determined. The weight differential corresponds to the amount of the wood consumed by the termites.

In this test, the macrolides according to the invention are very effective. 

1.-15. (canceled)
 16. A method of controlling wood pests, characterized in that a pesticidally active amount of a pesticide comprising, as pesticidally active compound, at least one macrolide, in free form or agrochemically utilizable salt form, as active ingredient and at least one auxiliary is applied to the pests or their environment.
 17. The method according to claim 16, characterized in that the active ingredient employed is abamectin, emamectin or spinosad, in free form or in agrochemically utilizable salt form.
 18. The method according to claim 17, characterized in that the active ingredient employed is emamectin as the benzoate salt.
 19. (canceled)
 20. A composition for controlling wood pests, characterized in that it comprises, as pesticidally active compound, at least one macrolide and at least one auxiliary.
 21. The method according to claim 16, characterized in that abamectin is employed.
 22. The method according to claim 16, characterized in that emamectin is employed.
 23. The method according to claim 16, wherein the wood pests are selected from the group consisting of the family Lyctidae, the family Apidae, and the family Anobiidae.
 24. The composition according to claim 20, characterized in that the active ingredient employed is abamectin, emamectin or spinosad, in free form or in agrochemically utilizable salt form.
 25. The composition according to claim 20, characterized in that the active ingredient employed is emamectin as the benzoate salt.
 26. The composition according to claim 20, characterized in that abamectin is employed.
 27. The composition according to claim 20, characterized in that emamectin is employed.
 28. The composition according to claim 20, wherein the wood pests are selected from the group consisting of the family Lyctidae, the family Apidae, and the family Anobiidae. 